Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.34 |
| ▸ | RAB9A | P51151 | 5/20 | 0.33 |
| ▸ | NPC1 | O15118 | 3/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 4/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 4/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.32 |
| ▸ | GAA | P10253 | 3/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20853539 | 1.00 | TSHR (0.36) | TSHRCYP1A2CYP2C9CYP2C19LMNA | |
| SCHEMBL15037477 | 1.00 | TSHR (0.36) | TSHRCYP1A2CYP2C9CYP2C19LMNA | |
| SCHEMBL15018540 | 0.97 | NPC1 (0.36) | TSHRCYP1A2CYP2C9CYP2C19LMNA | |
| SCHEMBL16369057 | 0.97 | NPC1 (0.36) | TSHRCYP1A2CYP2C9CYP2C19LMNA | |
| SCHEMBL15018539 | 0.97 | NPC1 (0.36) | TSHRCYP1A2CYP2C9CYP2C19LMNA | |
| SCHEMBL20853561 | 0.96 | MAPT (0.38) | TSHRCYP1A2CYP2C9CYP2C19LMNA | |
| SCHEMBL20853560 | 0.96 | MAPT (0.38) | TSHRCYP1A2CYP2C9CYP2C19LMNA | |
| SCHEMBL15037506 | 0.96 | MAPT (0.38) | TSHRCYP1A2CYP2C9CYP2C19LMNA | |
| SCHEMBL15018422 | 0.96 | MEN1 (0.36) | TSHRCYP1A2CYP2C9CYP2C19LMNA | |
| SCHEMBL16369060 | 0.96 | MEN1 (0.36) | TSHRCYP1A2CYP2C9CYP2C19LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2791250-B1 | PARTICULAR AZOMETHINE DIRECT DYES, DYE COMPOSITION COMPRISING AT LEAST ONE SUCH COMPOUND, IMPLEMENTATION PROCESS THEREFORE AND USE THEREOF | OREAL (FR) | 2019-04-03 | — | — | EP | claimed |
| EP-2791250-B1 | PARTICULAR AZOMETHINE DIRECT DYES, DYE COMPOSITION COMPRISING AT LEAST ONE SUCH COMPOUND, IMPLEMENTATION PROCESS THEREFORE AND USE THEREOF | OREAL (FR) | 2019-04-03 | — | — | EP | disclosed |