Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13013786 | 0.78 | — | — | |
| SCHEMBL18414215 | 0.77 | — | — | |
| SCHEMBL706106 | 0.77 | — | — | |
| SCHEMBL9491619 | 0.77 | — | — | |
| SCHEMBL2109735 | 0.74 | — | — | |
| SCHEMBL13716604 | 0.74 | OPRM1 (0.31) | — | |
| SCHEMBL11376220 | 0.73 | TSHR (0.46) | TSHR | |
| SCHEMBL28901694 | 0.72 | MEN1 (0.30) | — | |
| SCHEMBL26611106 | 0.71 | LMNA (0.32) | TSHR | |
| SCHEMBL26604616 | 0.71 | LMNA (0.32) | TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2364700-B1 | Compositions and methods to treat skin diseases characterized by cellular proliferation and angiogenesis | PALOMA PHARMACEUTICALS INC (US) | 2014-12-24 | — | — | EP | disclosed |