Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | CAPN1 | P07384 | 3/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16372048 | 0.93 | L3MBTL1 (0.40) | L3MBTL1ALDH1A1SMN1; SMN2CAPN1 | |
| SCHEMBL16369475 | 0.92 | L3MBTL1 (0.40) | L3MBTL1ALDH1A1SMN1; SMN2 | |
| SCHEMBL764478 | 0.86 | PPARA (0.41) | LMNAL3MBTL1 | |
| SCHEMBL16369484 | 0.81 | DDR2 (0.41) | L3MBTL1ALDH1A1SMN1; SMN2POLBRAB9A | |
| SCHEMBL765833 | 0.79 | L3MBTL1 (0.40) | L3MBTL1ALDH1A1SMN1; SMN2POLB | |
| SCHEMBL765547 | 0.79 | L3MBTL1 (0.40) | L3MBTL1ALDH1A1SMN1; SMN2POLB | |
| SCHEMBL764439 | 0.79 | L3MBTL1 (0.40) | L3MBTL1ALDH1A1SMN1; SMN2POLB | |
| SCHEMBL758301 | 0.79 | EPHX2 (0.41) | L3MBTL1ALDH1A1POLB | |
| SCHEMBL765102 | 0.78 | L3MBTL1 (0.39) | L3MBTL1ALDH1A1POLB | |
| SCHEMBL764502 | 0.77 | L3MBTL1 (0.38) | L3MBTL1ALDH1A1SMN1; SMN2POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8916589-B2 | Bradykinin B1-antagonists | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2014-12-23 | — | — | US | disclosed |