Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DDR2 | Q16832 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | CSF1R | P07333 | 1/20 | 0.39 |
| ▸ | GSK3B | P49841 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | PYGL | P06737 | 3/20 | 0.38 |
| ▸ | PYGM | P11217 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | MMP13 | P45452 | 1/20 | 0.37 |
| ▸ | RAF1 | P04049 | 1/20 | 0.37 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL765545 | 0.87 | DDR2 (0.44) | DDR2RAB9ACSF1RGSK3BL3MBTL1 | |
| SCHEMBL10121197 | 0.81 | DDR2 (0.41) | DDR2RAB9ACSF1RGSK3BALDH1A1 | |
| SCHEMBL765838 | 0.81 | P2RX7 (0.40) | DDR2RAB9AL3MBTL1ALDH1A1CYP1A2 | |
| SCHEMBL16372048 | 0.81 | L3MBTL1 (0.40) | L3MBTL1ALDH1A1SMN1; SMN2 | |
| SCHEMBL16369583 | 0.81 | LMNA (0.41) | RAB9AL3MBTL1ALDH1A1POLBSMN1; SMN2 | |
| SCHEMBL16369475 | 0.80 | L3MBTL1 (0.40) | L3MBTL1ALDH1A1SMN1; SMN2 | |
| SCHEMBL12238933 | 0.79 | P2RX7 (0.44) | RAB9AALDH1A1POLBSMN1; SMN2 | |
| SCHEMBL16369486 | 0.75 | BDKRB1 (0.51) | GSK3BCYP3A4SMN1; SMN2MMP13 | |
| SCHEMBL10121524 | 0.75 | BDKRB1 (0.44) | GSK3BSMN1; SMN2 | |
| SCHEMBL757814 | 0.75 | BDKRB1 (0.42) | POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8916589-B2 | Bradykinin B1-antagonists | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2014-12-23 | — | — | US | disclosed |