SCHEMBL1637017

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1637492	0.98	MAPT (0.45)	KDM4EATML3MBTL1MAPTALDH1A1
	SCHEMBL1637020	0.97	KDM4E (0.51)	KDM4EATML3MBTL1MAPTALDH1A1
	SCHEMBL9890470	0.97	MAPT (0.44)	KDM4EATML3MBTL1MAPTALDH1A1
	SCHEMBL26329809	0.96	KDM4E (0.50)	KDM4EATML3MBTL1MAPTALDH1A1
	SCHEMBL9890473	0.96	KDM4E (0.50)	KDM4EATML3MBTL1MAPTALDH1A1
	SCHEMBL1635406	0.95	KDM4E (0.47)	KDM4EATML3MBTL1MAPTALDH1A1
	SCHEMBL1636681	0.94	KDM4E (0.43)	KDM4EATML3MBTL1MAPTALDH1A1
	SCHEMBL16282952	0.94	MAPT (0.44)	KDM4EATML3MBTL1MAPTALDH1A1
	SCHEMBL1636722	0.94	MAPT (0.46)	KDM4EATML3MBTL1MAPTALDH1A1
	SCHEMBL18593819	0.93	KDM4E (0.44)	KDM4EATML3MBTL1MAPTALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 48 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.