Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GBA1 | P04062 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | MGLL | Q99685 | 4/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.39 |
| ▸ | FAAH | O00519 | 3/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.35 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.35 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7184113 | 0.71 | MGLL (0.43) | GBA1ALDH1A1MGLLPTGS1PTGS2 | |
| SCHEMBL8803997 | 0.70 | PLA2G2A (0.47) | GBA1ALDH1A1MGLLPTGS1PTGS2 | |
| SCHEMBL9789698 | 0.69 | MGLL (0.44) | GBA1ALDH1A1MGLLPTGS1PTGS2 | |
| SCHEMBL4017035 | 0.67 | MGLL (0.47) | GBA1ALDH1A1MGLLPTGS1PTGS2 | |
| SCHEMBL6779927 | 0.67 | MGLL (0.50) | GBA1ALDH1A1MGLLPTGS1PTGS2 | |
| SCHEMBL7098284 | 0.67 | GBA1 (0.42) | GBA1ALDH1A1MGLLPTGS1PTGS2 | |
| SCHEMBL4421172 | 0.66 | GBA1 (0.44) | GBA1ALDH1A1MGLLPTGS1PTGS2 | |
| SCHEMBL31601846 | 0.66 | MGLL (0.50) | GBA1ALDH1A1MGLLPTGS1PTGS2 | |
| SCHEMBL31602018 | 0.66 | MGLL (0.50) | GBA1ALDH1A1MGLLPTGS1PTGS2 | |
| SCHEMBL20441233 | 0.66 | MGLL (0.50) | GBA1ALDH1A1MGLLPTGS1PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015004610-A1 | 1,5-DIHYDROPYRROL-2-ONE DERIVATIVES AS INHIBITORS OF P53-MDM2/MDM4 PROTEIN-PROTEIN INTERACTION | ADAMED SP. Z O.O. (PL) | 2015-01-15 | — | — | WO | disclosed |