Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERN1 | O75460 | 4/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | CASP1 | P29466 | 1/20 | 0.43 |
| ▸ | PRKDC | P78527 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | AKR1B1 | P15121 | 4/20 | 0.39 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.38 |
| ▸ | NQO2 | P16083 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | CASP7 | P55210 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10750407 | 0.85 | ACHE (0.43) | ERN1ALDH1A1KDM4ETDP1MEN1 | |
| SCHEMBL6314730 | 0.85 | ERN1 (0.41) | ERN1ALDH1A1KDM4ETDP1MEN1 | |
| SCHEMBL10504348 | 0.84 | AKR1B1 (0.41) | ERN1ALDH1A1KDM4ETDP1MEN1 | |
| SCHEMBL29818620 | 0.84 | ERN1 (0.52) | ERN1ALDH1A1KDM4ETDP1MEN1 | |
| SCHEMBL29818735 | 0.82 | ERN1 (0.46) | ERN1ALDH1A1KDM4ETDP1MEN1 | |
| SCHEMBL5143502 | 0.81 | ERN1 (0.41) | ERN1ALDH1A1KDM4ETDP1MEN1 | |
| SCHEMBL4551009 | 0.80 | ALDH1A1 (0.44) | ERN1ALDH1A1KDM4ETDP1MEN1 | |
| SCHEMBL16684740 | 0.79 | ERN1 (0.43) | ERN1ALDH1A1KDM4ETDP1MEN1 | |
| SCHEMBL29690890 | 0.79 | ERN1 (0.43) | ERN1ALDH1A1KDM4ETDP1MEN1 | |
| SCHEMBL16684805 | 0.79 | ERN1 (0.49) | ERN1ALDH1A1KDM4ETDP1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1786828-B1 | NOVEL ENZYMATIC SUBSTRATES DERIVED FROM PHENOXAZINONE AND THEIR USE AS DEVELOPER IN DETECTION OF MICRO-ORGANISM WITH PEPTIDASE ACTIVITY | BIOMERIEUX SA (FR) | 2012-01-11 | — | — | EP | disclosed |
| US-7932050-B2 | Enzymatic substrates derived from phenoxazinone and their use as developers in detection of microorganisms with peptidase activity | BIOMERIEUX (FR) | 2011-04-26 | — | — | US | disclosed |
| US-20100028926-A1 | Novel enzymatic substrates derived from phenoxazinone and their use as developer in detection of microorganisms with peptidase activity | BIOMERIEUX (FR) | 2010-02-04 | — | — | US | disclosed |
| US-7626018-B2 | Enzymatic substrates derived from phenoxazinone and their use as developer in detection of microorganisms with peptidase activity | bioMérieux (FR) | 2009-12-01 | — | — | US | disclosed |
| US-20080293094-A1 | Novel Enzymatic Substrates Derived from Phenoxazinone and Their Use as Developer in Detection of Microorganisms with Peptidase Activity | BIOMERIEUX (FR) | 2008-11-27 | — | — | US | disclosed |
| EP-1786828-A1 | NOVEL ENZYMATIC SUBSTRATES DERIVED FROM PHENOXAZINONE AND THEIR USE AS DEVELOPER IN DETECTION OF MICRO-ORGANISM WITH PEPTIDASE ACTIVITY | BIOMERIEUX (FR) | 2007-05-23 | — | — | EP | disclosed |
| WO-2006030119-A1 | NOVEL ENZYMATIC SUBSTRATES DERIVED FROM PHENOXAZINONE AND THEIR USE AS DEVELOPER IN DETECTION OF MICRO-ORGANISM WITH PEPTIDASE ACTIVITY | bioMérieux (FR) | 2006-03-23 | — | — | WO | disclosed |
| EP-0507318-B1 | Benzothiazole derivative | EISAI CO LTD (JP) | 1997-09-10 | — | — | EP | disclosed |
| US-5635519-A | SUPPRESSANT FOR THE PRODUCTION OF LEUKOTRIENES AND THROMBOXANES; ENZYME INHIBITOR FOR 5-LIPOXYGENASE AND THROMBOXANE SYNTHETASE | EISAI CO., LTD. (JP) | 1997-06-03 | — | — | US | disclosed |
| US-5420144-A | Antiinflammatory agents and leukotriene inhibitors | EISAI CO., LTD. (JP) | 1995-05-30 | — | — | US | disclosed |
| US-5300518-A | Supressing leukotrien, lipoxygenase and thromoxane lipoxygenase and thromoxane | EISAI CO., LTD. (JP) | 1994-04-05 | — | — | US | disclosed |
| EP-0507318-A1 | Benzothiazole derivative | Eisai Co., Ltd. (JP) | 1992-10-07 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080293094-A1 | Novel Enzymatic Substrates Derived from Phenoxazinone and Their Use as Developer in Detection of Microorganisms with Peptidase Activity | PEPD, CTRL, PREP | ERN1 1531/4885ALDH1A1 639/4885KDM4E 2742/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.