SCHEMBL1637368

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL14039033	0.99	KDM4E (0.42)	KDM4EL3MBTL1ATMKMT2AALOX5
	SCHEMBL1637808	0.94	PRKDC (0.37)	KDM4EL3MBTL1ATMKMT2AALOX5
	SCHEMBL1637810	0.91	KDM4E (0.42)	KDM4EL3MBTL1ATMKMT2AALOX5
	SCHEMBL10165765	0.91	KDM4E (0.49)	KDM4EL3MBTL1ATMKMT2AALOX5
	SCHEMBL10038519	0.91	KDM4E (0.51)	KDM4EL3MBTL1ATMKMT2AALOX5
	SCHEMBL780958	0.89	KDM4E (0.41)	KDM4EL3MBTL1ATMKMT2AALOX5
	SCHEMBL1635727	0.89	KDM4E (0.49)	KDM4EL3MBTL1ATMKMT2AALOX5
	SCHEMBL781283	0.88	KDM4E (0.40)	KDM4EL3MBTL1ATMKMT2AALOX5
	SCHEMBL781446	0.88	KDM4E (0.40)	KDM4EL3MBTL1ATMKMT2AALOX5
	SCHEMBL15988960	0.88	KDM4E (0.45)	KDM4EL3MBTL1ATMKMT2AALOX5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 50 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.