Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAP | Q12884 | 2/20 | 0.44 |
| ▸ | STING1 | Q86WV6 | 4/20 | 0.41 |
| ▸ | AHCY | P23526 | 4/20 | 0.40 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.37 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.37 |
| ▸ | P2RY1 | P47900 | 2/20 | 0.36 |
| ▸ | DNPH1 | O43598 | 1/20 | 0.36 |
| ▸ | PRKAB2 | O43741 | 1/20 | 0.36 |
| ▸ | TRPM2 | O94759 | 1/20 | 0.36 |
| ▸ | LDHA | P00338 | 1/20 | 0.36 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.36 |
| ▸ | FBP1 | P09467 | 1/20 | 0.36 |
| ▸ | SRC | P12931 | 1/20 | 0.36 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.36 |
| ▸ | P2RY2 | P41231 | 1/20 | 0.36 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.36 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.36 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16368193 | 1.00 | FAP (0.44) | FAPSTING1AHCYADORA2AADORA3 | |
| SCHEMBL25566020 | 0.95 | FAP (0.42) | FAPSTING1AHCYADORA2AADORA3 | |
| SCHEMBL19993729 | 0.94 | FAP (0.45) | FAPSTING1AHCYADORA2AADORA3 | |
| SCHEMBL16368204 | 0.94 | FAP (0.45) | FAPSTING1AHCYADORA2AADORA3 | |
| SCHEMBL16368274 | 0.91 | FAP (0.47) | FAPSTING1AHCYADORA2AADORA3 | |
| SCHEMBL17359578 | 0.91 | FAP (0.47) | FAPSTING1AHCYADORA2AADORA3 | |
| SCHEMBL16368080 | 0.90 | FAP (0.33) | FAPSTING1ADORA2ANT5E | |
| SCHEMBL17359557 | 0.89 | FAP (0.50) | FAPSTING1AHCYADORA2AADORA3 | |
| SCHEMBL17358556 | 0.87 | FAP (0.44) | FAPSTING1AHCYADORA2AADORA3 | |
| SCHEMBL16647421 | 0.86 | AHCY (0.38) | AHCYADORA2AADORA3P2RY1DNPH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014209979-A1 | SUBSTITUTED NUCLEOSIDES, NUCLEOTIDES AND ANALOGS THEREOF | ALIOS BIOPHARMA, INC. (US) | 2014-12-31 | — | — | WO | disclosed |