O-Xylene

O-Xylene

SCHEMBL163751

Cc1ccccc1C.N=C=O

nearest known ligand 0.62

Full drug profile on Sugi Atlas →

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
TSHR P16473 4/20 0.62
ACHE P22303 3/20 0.62
ALDH1A1 P00352 6/20 0.42
CA1 P00915 2/20 0.41
CA2 P00918 2/20 0.41
CA7 P43166 2/20 0.41
CA9 Q16790 2/20 0.41
TDP1 Q9NUW8 2/20 0.39
CYP3A4 P08684 1/20 0.39
HSD17B10 Q99714 1/20 0.39
CYP1A2 P05177 2/20 0.38
CYP2A6 P11509 2/20 0.38
NPC1 O15118 1/20 0.37
RAB9A P51151 1/20 0.37
HPGD P15428 2/20 0.36
MGLL Q99685 1/20 0.36
LMNA P02545 1/20 0.35
ALOX12 P18054 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
O-Xylene SCHEMBL3683886 1.00 TSHR (0.62) TSHRACHEALDH1A1CA1CA2
O-Xylene SCHEMBL29297 1.00 TSHR (0.62) TSHRACHEALDH1A1CA1CA2
O-Xylene SCHEMBL29802653 1.00 TSHR (0.62) TSHRACHEALDH1A1CA1CA2
O-Xylene SCHEMBL29860873 1.00 TSHR (0.62) TSHRACHEALDH1A1CA1CA2
O-Xylene SCHEMBL29851191 1.00 TSHR (0.62) TSHRACHEALDH1A1CA1CA2
O-Xylene SCHEMBL31425598 1.00 TSHR (0.62) TSHRACHEALDH1A1CA1CA2
O-Xylene SCHEMBL1048806 0.97 TSHR (0.59) TSHRACHEALDH1A1CA1CA2
O-Xylene SCHEMBL7090404 0.97 TSHR (0.59) TSHRACHEALDH1A1CA1CA2
O-Xylene SCHEMBL27736573 0.97 TSHR (0.59) TSHRACHEALDH1A1CA1CA2
O-Xylene SCHEMBL27602605 0.97 TSHR (0.59) TSHRACHEALDH1A1CA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 600 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4603478-A1 XYLENE DIISOCYANATE COMPOSITION AND PREPARATION METHOD THEREFOR Hanwha Solutions Corporation (KR) 2025-08-20 EP claimed
CN-119907820-A Isocyanate composition 韩华思路信(株) 2025-04-29 CN claimed
CN-111168912-B Preparation method and product of polyimide-aluminum heat-insulation sound-absorption composite foam 哈尔滨工程大学 2025-03-04 CN claimed
CN-118440389-A Preparation method of polyurethane microporous elastomer composite material for railway sleeper 苏州智源颢联新材料科技有限公司 2024-08-06 CN claimed
CN-118317988-A Isocyanate composition and process for producing the same 韩华思路信(株) 2024-07-09 CN claimed
WO-2024106985-A1 XYLENE DIISOCYANATE COMPOSITION AND PREPARATION METHOD THEREFOR 한화솔루션 주식회사 2024-05-23 WO claimed
CN-117659346-A Novel high-toughness recyclable room-temperature self-repairing polyurethane and preparation method thereof 电子科技大学长三角研究院(湖州) 2024-03-08 CN claimed
CN-115181535-B Ultraviolet light-moisture dual-curing polyurethane hot melt adhesive and preparation method thereof 苏州合邦鑫材科技有限公司 2024-01-12 CN claimed
CN-117304863-A LED-UV (light-emitting diode-ultraviolet) curing type strippable protective adhesive as well as preparation method and application thereof 天津科技大学 2023-12-29 CN claimed
CN-116970377-A High-temperature-resistant filtrate reducer for drilling fluid and preparation method thereof 廊坊庆兴化工有限公司 2023-10-31 CN claimed
CN-107629189-A A kind of preparation and application of low-viscosity polyurethane acrylate 天津久日新材料股份有限公司 2018-01-26 CN claimed
CN-103910812-B Beta-cyclodextrin derivative and its preparation method and many ureas key cyclodextrin chiral prepared therefrom are fixed phase GUANGZHOU YANCHUANG BIO-TECH DEVELOPMENT CO., LTD. (CN) 2016-05-11 CN claimed
CN-100575382-C Water-dispersible polyisocyanate composition containing urea and/or biuret and use thereof DADONG RESIN CHEMICAL CO LTD 2009-12-30 CN claimed
CN-100371390-C Water dispersible polyisocyanate composition and use thereof DADONG RESIN CHEMICAL CO LTD (CN) 2008-02-27 CN claimed
US-7196154-B2 Method of producing polymer resins LIGHT BLACK INC. (JP) 2007-03-27 US claimed
CN-1590431-A Water-dispersible polyisocyanate composition containing urea and/or biuret and use thereof DADONG RESIN CHEMICAL CO LTD (CN) 2005-03-09 CN claimed
CN-1470564-A water dispersible polyisocyanate composition and use thereof ����֬��ѧ�ɷ����޹�˾ 2004-01-28 CN claimed
US-20020166630-A1 Method of producing polymer resins LIGHT BLACK U.S.A., INC. 2002-11-14 US claimed
CN-1207501-A Lenses obtained from high-speed polymerizable resin composition MITSUI CHEMICALS INC (JP) 1999-02-10 CN claimed
CN-86108166-A Improved products and production method thereof 1987-07-22 CN claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020166630-A1 Method of producing polymer resins PARG, PNMT, ALKBH5 TSHR 3617/4885ACHE 508/4885ALDH1A1 2640/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.