Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.48 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.41 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.40 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.40 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.40 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.40 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.39 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.38 |
| ▸ | MC4R | P32245 | 1/20 | 0.37 |
| ▸ | MC5R | P33032 | 1/20 | 0.37 |
| ▸ | MC3R | P41968 | 1/20 | 0.37 |
| ▸ | MC1R | Q01726 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10307786 | 0.98 | CYP1A2 (0.52) | CYP1A2CYP2C19EPHX1PLA2G4BCYP2D6 | |
| Cpi 613 SCHEMBL13333201 | 0.89 | CYP2C19 (0.59) | CYP2C19PTGER1PTGER4PTGER3PTGER2 | |
| Cpi 613 SCHEMBL1062218 | 0.89 | CYP2C19 (0.59) | CYP2C19PTGER1PTGER4PTGER3PTGER2 | |
| SCHEMBL22299081 | 0.88 | CYP2C19 (0.58) | CYP2C19PTGER1PTGER4PTGER3PTGER2 | |
| SCHEMBL17381514 | 0.88 | CYP2C19 (0.58) | CYP2C19PTGER1PTGER4PTGER3PTGER2 | |
| SCHEMBL10307745 | 0.84 | CYP2C19 (0.50) | CYP2C19PTGER1PTGER4PTGER3PTGER2 | |
| SCHEMBL10307764 | 0.81 | CYP2C19 (0.47) | CYP2C19PTGER1PTGER4PTGER3PTGER2 | |
| SCHEMBL20395792 | 0.81 | CYP2C19 (0.63) | CYP2C19PTGER1PTGER4PTGER3PTGER2 | |
| SCHEMBL10307777 | 0.81 | CYP2C19 (0.52) | CYP2C19EPHX1PTGER1PTGER4PTGER3 | |
| SCHEMBL10307784 | 0.81 | CYP2C19 (0.44) | CYP2C19EPHX1PTGER1PTGER4PTGER3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150011633-A1 | PHARMACEUTICAL FORMULATIONS CONTAINING LIPOIC ACID DERIVATIVES | CORNERSTONE PHARMACEUTICALS, INC. (US) | 2015-01-08 | — | — | US | disclosed |
| US-20150011633-A1 | PHARMACEUTICAL FORMULATIONS CONTAINING LIPOIC ACID DERIVATIVES | CORNERSTONE PHARMACEUTICALS, INC. (US) | 2015-01-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150011633-A1 | PHARMACEUTICAL FORMULATIONS CONTAINING LIPOIC ACID DERIVATIVES | LIPA, LIPC, TTPA | CYP1A2 1104/4885CYP2C19 295/4885EPHX1 3489/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.