SCHEMBL1637559

SCHEMBL1637559

C[SiH](C)O[Si](C)(C)c1ccc(N)cc1

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 3/20 0.35
MEN1 O00255 1/20 0.35
KMT2A Q03164 1/20 0.35
TDP1 Q9NUW8 7/20 0.34
MAPK1 P28482 2/20 0.34
ALDH1A1 P00352 6/20 0.33
CYP3A4 P08684 4/20 0.33
ACHE P22303 1/20 0.33
TSHR P16473 2/20 0.32
TP53 P04637 3/20 0.32
NPC1 O15118 2/20 0.32
RAB9A P51151 2/20 0.32
KDM4E B2RXH2 1/20 0.32
HPGD P15428 1/20 0.32
NFKB1 P19838 1/20 0.32
NFKB2 Q00653 1/20 0.32
RELA Q04206 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
HSD17B10 Q99714 1/20 0.32
TEAD4 Q15561 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16749894 0.89 HPGD (0.31) HPGD
SCHEMBL20679531 0.81
SCHEMBL15677724 0.80 ACHE (0.36) MEN1KMT2ATDP1ALDH1A1ACHE
SCHEMBL7649982 0.78 ESR1 (0.45) MAPTMEN1KMT2AALDH1A1CYP3A4
SCHEMBL4795729 0.77 ESR1 (0.37)
SCHEMBL28390398 0.77 CA1 (0.46) MAPTMEN1KMT2ATDP1MAPK1
SCHEMBL127697 0.77 MAPT (0.42) MAPTMEN1KMT2ATDP1MAPK1
SCHEMBL3391059 0.76 CYP3A4 (0.39) MAPTMEN1KMT2ATDP1ALDH1A1
SCHEMBL1172627 0.75 TDP1 (0.44) MAPTMEN1KMT2ATDP1MAPK1
SCHEMBL124891 0.73 MAPT (0.38) MAPTMEN1KMT2ATDP1MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-10087825-A None JP disclosed
CN-115956301-A Display device and method for manufacturing display device 东丽株式会社 2023-04-11 CN disclosed
CN-115636847-A Modified silane coupling agent, preparation method thereof and application of modified silane coupling agent in positive photosensitive resin composition 明士(北京)新材料开发有限公司 2023-01-24 CN disclosed
CN-114957660-A Polyimide resin composition, polyimide resin adhesive layer, laminate, and method for producing electronic component 新应材股份有限公司 2022-08-30 CN disclosed
CN-114721223-A Photosensitive resin, photosensitive resin composition, cured product, pattern forming method, and integrated circuit device 华为技术有限公司 2022-07-08 CN disclosed
CN-107924125-B Positive photosensitive resin composition, uncured and cured pattern formed therefrom, semiconductor device using the same, and method for manufacturing the same 东丽株式会社 2020-12-25 CN disclosed
CN-108779331-B Resin composition, cured relief pattern thereof, and method for producing semiconductor electronic component or semiconductor device using same 东丽株式会社 2020-08-25 CN disclosed
US-20190033714-A1 RESIN COMPOSITION, CURED RELIEF PATTERN THEREOF, AND METHOD FOR MANUFACTURING SEMICONDUCTOR ELECTRONIC COMPONENT OR SEMICONDUCTOR EQUIPMENT USING THE SAME TORAY INDUSTRIES, INC. (JP) 2019-01-31 US disclosed
US-7932412-B2 Method of manufacturing an aminoaryl-containing organosilicon compound and method of manufacturing an intermediate product of the aforementioned compound DOW CORNING TORAY CO., LTD. (JP) 2011-04-26 US disclosed
EP-1797103-B1 Preparation of an aminoaryl-containing organosilicon compound and intermediate used in its preparation DOW CORNING TORAY CO LTD (JP) 2010-12-29 EP disclosed
EP-1797103-A2 PREPARATION OF AN AMINOARYL-CONTAINING ORGANOSILICON COMPOUND AND METHODS OF PREPARAING INTERMEDIATES USED IN ITS PREPARATION Dow Corning Toray Co., Ltd. (JP) 2007-06-20 EP disclosed
WO-2006038707-A2 PREPARATION OF AN AMINOARYL-CONTAINING ORGANOSILICON COMPOUND AND METHODS OF PREPARAING INTERMEDIATES USED IN ITS PREPARATRION DOW CORNING TORAY CO., LTD. (JP) 2006-04-13 WO disclosed
JP-H1087825-A LIQUID CRYSTAL ALIGNING AGENT SUMITOMO BAKELITE CO LTD 1998-04-07 JP disclosed
US-5633112-A Photosensitive resin composition containing a carboxylic acid polymer, photoacid generator and secondary or tertiary aliphatic amine HITACHI, LTD. (JP) 1997-05-27 US disclosed