SCHEMBL127697

SCHEMBL127697

C[Si](C)(O[Si](C)(C)c1ccc(N)cc1)c1ccc(N)cc1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 5/20 0.42
MEN1 O00255 2/20 0.42
KMT2A Q03164 2/20 0.42
TDP1 Q9NUW8 7/20 0.40
MAPK1 P28482 5/20 0.40
ACHE P22303 2/20 0.39
ALDH1A1 P00352 11/20 0.39
CYP3A4 P08684 5/20 0.39
TSHR P16473 3/20 0.38
TP53 P04637 3/20 0.36
NPC1 O15118 3/20 0.36
RAB9A P51151 3/20 0.36
TEAD4 Q15561 1/20 0.36
SMN1; SMN2 Q16637 3/20 0.35
HSD17B10 Q99714 2/20 0.35
HPGD P15428 2/20 0.35
KDM4E B2RXH2 1/20 0.35
NFKB1 P19838 1/20 0.35
NFKB2 Q00653 1/20 0.35
RELA Q04206 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL124891 0.90 MAPT (0.38) MAPTMEN1KMT2ATDP1MAPK1
SCHEMBL26185015 0.88 MAPT (0.36) MAPTMEN1KMT2ATDP1MAPK1
SCHEMBL23879680 0.88 MAPT (0.36) MAPTMEN1KMT2ATDP1MAPK1
SCHEMBL9472831 0.83 TDP1 (0.32) MAPTMEN1KMT2ATDP1MAPK1
SCHEMBL1172627 0.82 TDP1 (0.44) MAPTMEN1KMT2ATDP1MAPK1
SCHEMBL2616663 0.77 TDP1 (0.45) MAPTMEN1KMT2ATDP1MAPK1
SCHEMBL1637559 0.77 MAPT (0.35) MAPTMEN1KMT2ATDP1MAPK1
SCHEMBL9743132 0.76 ACHE (0.44) MEN1KMT2ATDP1ACHEALDH1A1
SCHEMBL16773965 0.75 IDO1 (0.39) TDP1ALDH1A1TP53NPC1RAB9A
SCHEMBL952880 0.75 MAPT (0.38) MAPTMEN1KMT2ATDP1MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 186 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119431784-A Alkali-soluble polyimide precursor, method for preparing the same, and positive photosensitive resin composition 万华化学集团股份有限公司 2025-02-14 CN claimed
WO-2024216910-A1 HIGH-CHEMICAL-RESISTANCE POSITIVE PHOTOSENSITIVE RESIN COMPOSITION, PREPARATION METHOD THEREFOR, AND USE THEREOF 明士(北京)新材料开发有限公司 2024-10-24 WO claimed
EP-2949719-B1 ADHESIVE COMPOSITION TORAY INDUSTRIES (JP) 2022-11-09 EP claimed
US-8722758-B2 Water soluble polyimide resin, its preparation and use CHANG CHUN PLASTICS CO., LTD. (TW) 2014-05-13 US claimed
US-8084512-B2 Water soluble photosensitive polymide polymer, its preparation and photoresist containing the same CHANG CHUN PLASTICS CO., LTD. (TW) 2011-12-27 US claimed
US-20110172324-A1 NOVEL WATER SOLUBLE POLYIMIDE RESIN, ITS PREPARATION AND USE CHANG CHUN PLASTICS CO., LTD. (TW) 2011-07-14 US claimed
US-20100167208-A1 WATER SOLUBLE PHOTOSENSITIVE POLYMIDE POLYMER, ITS PREPARATION AND PHOTORESIST CONTAINING THE SAME CHANG CHUN PLASTICS CO., LTD. (TW) 2010-07-01 US claimed
US-5286890-A Aromatic amine terminated silicone monomers, oligomers, and polymers therefrom HUGHES AIRCRAFT COMPANY (US) 1994-02-15 US claimed
JP-63264339-A None JP disclosed
US-12604529-B2 Display device and method for manufacturing display device TORAY INDUSTRIES, INC. (JP) 2026-04-14 US disclosed
US-20260035513-A1 RESIN COMPOSITION, REINFORCED COMPOSITE MATERIAL, SHAPED PRODUCT, AND METHOD OF RECOVERING REINFORCING FIBER FROM REINFORCED COMPOSITE MATERIAL ASAHI KASEI KABUSHIKI KAISHA (JP) 2026-02-05 US disclosed
EP-4578892-A1 RESIN COMPOSITION, COMPOSITE REINFORCING MATERIAL, MOLDED BODY, AND METHOD FOR RECOVERING REINFORCING FIBERS FROM COMPOSITE REINFORCING MATERIAL Asahi Kasei Kabushiki Kaisha (JP) 2025-07-02 EP disclosed
CN-119620472-A Liquid crystal aligning agent, liquid crystal alignment film, and liquid crystal display element using same 日产化学株式会社 2025-03-14 CN disclosed
CN-119431784-A Alkali-soluble polyimide precursor, method for preparing the same, and positive photosensitive resin composition 万华化学集团股份有限公司 2025-02-14 CN disclosed
EP-0328901-B1 SPIRO(BIS)INDANE BIS(CARBOXYPHENYL ETHERS) AND DERIVATIVES THEREOF GENERAL ELECTRIC COMPANY (US) 1992-04-22 EP disclosed
EP-0328901-A1 Spiro(bis)indane bis(carboxyphenyl ethers) and derivatives thereof GENERAL ELECTRIC COMPANY (US) 1989-08-23 EP disclosed
US-4814496-A Spiro(bis)indane bis(carboxyphenyl ethers) and derivatives thereof GENERAL ELECTRIC COMPANY (US) 1989-03-21 US disclosed
JP-S63264339-A MANUFACTURE OF FLEXIBLE WIRING BOARD SUMITOMO ELECTRIC IND LTD 1988-11-01 JP disclosed
EP-0233900-A1 FLAME RETARDANT WIRE COATING COMPOSITIONS GENERAL ELECTRIC COMPANY (US) 1987-09-02 EP disclosed
WO-1987000846-A1 FLAME RETARDANT WIRE COATING COMPOSITIONS GENERAL ELECTRIC COMPANY (US) 1987-02-12 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260035513-A1 RESIN COMPOSITION, REINFORCED COMPOSITE MATERIAL, SHAPED PRODUCT, AND METHOD OF RECOVERING REINFORCING FIBER FROM REINFORCED COMPOSITE MATERIAL TAF1, TAF1L, TAF9 MAPT 50/4885MEN1 3916/4885KMT2A 2237/4885
US-20110172324-A1 NOVEL WATER SOLUBLE POLYIMIDE RESIN, ITS PREPARATION AND USE ARID2, PUF60, PADI4 MAPT 1656/4885MEN1 4043/4885KMT2A 316/4885
US-12604529-B2 Display device and method for manufacturing display device CAD, EED, ADIPOR1 MAPT 464/4885MEN1 2358/4885KMT2A 1712/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.