SCHEMBL1637576

SCHEMBL1637576

Br[C](Br)C(Br)(Br)c1ccccc1Br

nearest known ligand 0.41

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
CA1 P00915 2/20 0.41
CA2 P00918 2/20 0.41
CA5A P35218 1/20 0.41
CA9 Q16790 1/20 0.41
ALDH1A1 P00352 3/20 0.35
GAA P10253 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
MAPK1 P28482 1/20 0.32
TSHR P16473 1/20 0.31
TDP1 Q9NUW8 1/20 0.31
BBOX1 O75936 1/20 0.31
EHMT2 Q96KQ7 1/20 0.31
EHMT1 Q9H9B1 1/20 0.31
HSD11B1 P28845 2/20 0.30
L3MBTL1 Q9Y468 1/20 0.30
CA4 P22748 1/20 0.30
CA6 P23280 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27772530 0.74 CA1 (0.43) CA1CA2CA5ACA9ALDH1A1
SCHEMBL130273 0.73 CA1 (0.37) CA1CA2CA5ACA9ALDH1A1
SCHEMBL7248359 0.73 CA1 (0.37) CA1CA2CA5ACA9ALDH1A1
SCHEMBL2266185 0.73 CA1 (0.46) CA1CA2CA5ACA9ALDH1A1
SCHEMBL25541474 0.72 CA1 (0.42) CA1CA2CA5ACA9ALDH1A1
Nitrogen SCHEMBL9028084 0.70 CA1 (0.50) CA1CA2CA5ACA9ALDH1A1
Methyl Alcohol SCHEMBL6773345 0.70 ALDH1A1 (0.52) CA1CA2CA5ACA9ALDH1A1
SCHEMBL28124531 0.70 CA1 (0.45) CA1CA2CA5ACA9ALDH1A1
SCHEMBL25620367 0.70 CA1 (0.41) CA1CA2CA5ACA9ALDH1A1
SCHEMBL30530486 0.70 ALDH1A1 (0.41) CA1CA2CA5ACA9ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1730209-B1 BROMINATED POLYMERS, AND FIRE RETARDANT ARTICLES COMPRISING THEM B G POLYMERS A C A LTD (IL) 2011-10-05 EP disclosed
US-7932338-B2 Brominated polymers, and fire retardant articles comprising them BROMINE COMPOUNDS LTD. (IL) 2011-04-26 US disclosed
US-20070167550-A1 Brominated polymers, and fire retardant articles comprising them BROMINE COMPOUNDS LTD. (IL) 2007-07-19 US disclosed
EP-1730209-A1 BROMINATED POLYMERS, AND FIRE RETARDANT ARTICLES COMPRISING THEM B.G. Polymers (IL) 2006-12-13 EP disclosed
WO-2005070980-A1 BROMINATED POLYMERS, AND FIRE RETARDANT ARTICLES COMPRISING THEM B.G. POLYMERS (IL) 2005-08-04 WO disclosed