SCHEMBL7248359

SCHEMBL7248359

O=C(O)C(Br)=C(Br)C(Br)(Br)c1ccccc1Br

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA1 P00915 1/20 0.37
CA2 P00918 1/20 0.37
CA5A P35218 1/20 0.37
CA9 Q16790 1/20 0.37
KMT2A Q03164 4/20 0.36
MEN1 O00255 2/20 0.36
LMNA P02545 2/20 0.36
HTT P42858 2/20 0.36
NPC1 O15118 1/20 0.36
RAB9A P51151 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.34
PDE2A O00408 1/20 0.33
MAPT P10636 1/20 0.33
EGFR P00533 1/20 0.33
MGLL Q99685 1/20 0.32
PDK1 Q15118 1/20 0.32
PDK2 Q15119 1/20 0.32
PDK3 Q15120 1/20 0.32
PDK4 Q16654 1/20 0.32
HSD11B1 P28845 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL130273 0.78 CA1 (0.37) CA1CA2CA5ACA9KMT2A
SCHEMBL1637576 0.73 CA1 (0.41) CA1CA2CA5ACA9SMN1; SMN2
SCHEMBL5199900 0.68 CYP2C9 (0.50) CA1CA2CA5ACA9KMT2A
SCHEMBL3533731 0.68 CYP2C19 (0.38) CA1CA2CA5ACA9KMT2A
SCHEMBL1828511 0.67 PDK1 (0.41) CA1CA2CA5ACA9KMT2A
SCHEMBL4640551 0.67 CA1 (0.48) CA1CA2CA5ACA9KMT2A
SCHEMBL2967568 0.67 CA1 (0.40) CA1CA2CA5ACA9KMT2A
SCHEMBL3136256 0.67 KMT2A (0.41) CA1CA2CA5ACA9KMT2A
SCHEMBL28844144 0.64 TAS2R14 (0.31)
SCHEMBL22636306 0.64 CYP1A2 (0.43) CA1CA2CA5ACA9KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0595408-B1 A method of improving the surface compatibility of polypropylene and its compositions and articles obtained thereby BROMINE COMPOUNDS LTD (IL) 1997-02-12 EP claimed
EP-0481126-B1 Flame retarded polycarbonates BROMINE COMPOUNDS LTD (IL) 1996-03-06 EP claimed
US-5430106-A Thermoprocessing with aromatic ring-polybrominated olefinic compound in absence of free radical initiators; bonding strength BROMINE COMPOUNDS LTD. (IL) 1995-07-04 US claimed
EP-0595408-A1 A method of improving the surface compatibility of polypropylene and its compositions and articles obtained thereby Bromine Compounds Ltd. (IL) 1994-05-04 EP claimed
US-5239021-A Transparent BROMINE COMPOUNDS LIMITED (IL) 1993-08-24 US claimed
EP-0481126-A2 Flame retarded polycarbonates Bromine Compounds Ltd. (IL) 1992-04-22 EP claimed
US-5045618-A Pentabromobenzyl Acrylate-Metal Acrylate Copolymers BROMINE COMPOUNDS LTD. (IL) 1991-09-03 US claimed
JP-6200065-A None JP disclosed
US-6632870-B2 Mixture containing polyhalogenated trimethylphenyl indanecompound BROMINE COMPOUNDS LTD. (IL) 2003-10-14 US disclosed
US-20010021742-A1 Flame-retarded transparent plastics BROMINE COMPOUNDS LTD. (IL) 2001-09-13 US disclosed
EP-0595408-B1 A method of improving the surface compatibility of polypropylene and its compositions and articles obtained thereby BROMINE COMPOUNDS LTD (IL) 1997-02-12 EP disclosed
EP-0481126-B1 Flame retarded polycarbonates BROMINE COMPOUNDS LTD (IL) 1996-03-06 EP disclosed
US-5430106-A Thermoprocessing with aromatic ring-polybrominated olefinic compound in absence of free radical initiators; bonding strength BROMINE COMPOUNDS LTD. (IL) 1995-07-04 US disclosed
JP-H06200065-A IMPROVEMENT OF SURFACE COMPATIBILITY OF POLYPROPYLENE AND ITS COMPOSITION AND ARTICLE OBTAINED THEREBY BROMINE COMPOUNDS LTD 1994-07-19 JP disclosed
EP-0595408-A1 A method of improving the surface compatibility of polypropylene and its compositions and articles obtained thereby Bromine Compounds Ltd. (IL) 1994-05-04 EP disclosed
US-5239021-A Transparent BROMINE COMPOUNDS LIMITED (IL) 1993-08-24 US disclosed
US-5239021-A Transparent BROMINE COMPOUNDS LIMITED (IL) 1993-08-24 US disclosed
EP-0481126-A2 Flame retarded polycarbonates Bromine Compounds Ltd. (IL) 1992-04-22 EP disclosed
EP-0481126-A2 Flame retarded polycarbonates Bromine Compounds Ltd. (IL) 1992-04-22 EP disclosed