SCHEMBL16375901

SCHEMBL16375901

CCS(=O)(=O)c1ccc(NOC)nc1-c1nc2cc(C(F)(F)F)ccc2o1

nearest known ligand 0.46

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
AGPAT2 O15120 2/20 0.43
UTRN P46939 5/20 0.43
PTPN2 P17706 4/20 0.40
PTPN1 P18031 4/20 0.40
PTPN5 P54829 4/20 0.40
HSPD1 P10809 2/20 0.40
HSPE1 P61604 2/20 0.40
CETP P11597 1/20 0.39
MEN1 O00255 1/20 0.38
MAPT P10636 1/20 0.38
KMT2A Q03164 1/20 0.38
HDAC6 Q9UBN7 2/20 0.37
HDAC3 O15379 1/20 0.37
HDAC1 Q13547 1/20 0.37
HDAC2 Q92769 1/20 0.37
HDAC8 Q9BY41 1/20 0.37
PPARG P37231 1/20 0.37
CYP1A2 P05177 1/20 0.36
AHR P35869 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18327930 0.86 ALDH1A1 (0.43) AGPAT2UTRNMEN1MAPTKMT2A
SCHEMBL17733125 0.83 UTRN (0.42) AGPAT2UTRNPTPN2PTPN1PTPN5
Methoxyamine SCHEMBL17726160 0.83 UTRN (0.46) AGPAT2UTRNPTPN2PTPN1PTPN5
SCHEMBL16375186 0.83 AGPAT2 (0.46) AGPAT2UTRNPTPN2PTPN1PTPN5
SCHEMBL16375381 0.83 UTRN (0.44) AGPAT2UTRNPTPN2PTPN1PTPN5
SCHEMBL17726150 0.82 AGPAT2 (0.44) AGPAT2PTPN2PTPN1PTPN5HSPD1
SCHEMBL16376065 0.79 PPARG (0.39) AGPAT2PTPN2PTPN1PTPN5HSPD1
SCHEMBL15933541 0.79 UTRN (0.42) AGPAT2UTRNPTPN2PTPN1PTPN5
SCHEMBL29431584 0.79 UTRN (0.42) AGPAT2UTRNPTPN2PTPN1PTPN5
SCHEMBL16376341 0.78 UTRN (0.42) AGPAT2UTRNPTPN2PTPN1PTPN5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3018130-B1 FUSED HETEROCYCLIC COMPOUND AND PEST CONTROL USE THEREOF SUMITOMO CHEMICAL CO (JP) 2021-08-04 EP disclosed
US-9920050-B2 Fused heterocyclic compound and pest control use thereof SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2018-03-20 US disclosed
US-20160368915-A1 FUSED HETEROCYCLIC COMPOUND AND PEST CONTROL USE THEREOF SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2016-12-22 US disclosed
WO-2015002211-A1 FUSED HETEROCYCLIC COMPOUND AND PEST CONTROL USE THEREOF 住友化学株式会社 (JP) 2015-01-08 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160368915-A1 FUSED HETEROCYCLIC COMPOUND AND PEST CONTROL USE THEREOF CBR3, NOX5, CBR1 AGPAT2 2710/4885UTRN 4514/4885PTPN2 2957/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.