SCHEMBL16376115

SCHEMBL16376115

CC(C)/C(=N\c1cccc2cccc(N=C(N(C)C)N(C)C)c12)N(C)C

nearest known ligand 0.34

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
HTR2A P28223 2/20 0.34
SIGMAR1 Q99720 3/20 0.33
KDM4E B2RXH2 1/20 0.32
GAA P10253 1/20 0.32
MAPT P10636 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL676864 0.86 KDM4E (0.41) HTR2ASIGMAR1KDM4EGAAMAPT
Hydrochloric Acid SCHEMBL5746772 0.84 MAPT (0.40) HTR2ASIGMAR1KDM4EGAAMAPT
SCHEMBL5747124 0.81 CYP3A4 (0.40) HTR2ASIGMAR1KDM4EGAAMAPT
SCHEMBL5745827 0.79 KDM4E (0.39) HTR2ASIGMAR1KDM4EGAAMAPT
SCHEMBL13967904 0.74 KDM4E (0.32) SIGMAR1KDM4EGAAMAPT
SCHEMBL13967928 0.74 KDM4E (0.32) SIGMAR1KDM4EGAAMAPT
SCHEMBL13967926 0.73 KDM4E (0.34) SIGMAR1KDM4EGAAMAPT
SCHEMBL13967975 0.73 SIGMAR1 (0.45) SIGMAR1
SCHEMBL13967982 0.72 KDM4E (0.33) SIGMAR1KDM4EGAAMAPT
SCHEMBL13169288 0.72 SIGMAR1 (0.32) SIGMAR1KDM4EGAAMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11059995-B2 Film forming composition MERCK PATENT GMBH (DE) 2021-07-13 US disclosed
US-20200377761-A1 FILM FORMING COMPOSITION MERCK PATENT GMBH (DE) 2020-12-03 US disclosed
US-9323153-B2 Actinic ray-sensitive or radiation-sensitive resin composition, and, actinic ray-sensitive or radiation-sensitive film and pattern forming method, each using the same FUJIFILM CORPORATION (JP) 2016-04-26 US disclosed
US-9323153-B2 Actinic ray-sensitive or radiation-sensitive resin composition, and, actinic ray-sensitive or radiation-sensitive film and pattern forming method, each using the same FUJIFILM CORPORATION (JP) 2016-04-26 US disclosed
US-20150004533-A1 ACTINIC RAY-SENSITIVE OR RADIATION-SENSITIVE RESIN COMPOSITION, AND, ACTINIC RAY-SENSITIVE OR RADIATION-SENSITIVE FILM AND PATTERN FORMING METHOD, EACH USING THE SAME FUJIFILM CORPORATION (JP) 2015-01-01 US disclosed
US-20150004533-A1 ACTINIC RAY-SENSITIVE OR RADIATION-SENSITIVE RESIN COMPOSITION, AND, ACTINIC RAY-SENSITIVE OR RADIATION-SENSITIVE FILM AND PATTERN FORMING METHOD, EACH USING THE SAME FUJIFILM CORPORATION (JP) 2015-01-01 US disclosed