Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.32 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.31 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.31 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.31 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.31 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.31 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.31 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL676864 | 0.80 | KDM4E (0.41) | SIGMAR1MAPTKDM4EGAA | |
| SCHEMBL5747124 | 0.78 | CYP3A4 (0.40) | SIGMAR1MAPTKDM4EGAA | |
| Hydrochloric Acid SCHEMBL5746772 | 0.78 | MAPT (0.40) | SIGMAR1MAPTKDM4EGAA | |
| SCHEMBL5745827 | 0.77 | KDM4E (0.39) | SIGMAR1MAPTKDM4EGAA | |
| SCHEMBL13967926 | 0.74 | KDM4E (0.34) | SIGMAR1MAPTKDM4EGAA | |
| SCHEMBL16376115 | 0.72 | HTR2A (0.34) | SIGMAR1MAPTKDM4EGAA | |
| SCHEMBL13967975 | 0.71 | SIGMAR1 (0.45) | SIGMAR1 | |
| SCHEMBL13967982 | 0.70 | KDM4E (0.33) | SIGMAR1MAPTKDM4EGAA | |
| SCHEMBL3245718 | 0.70 | SIGMAR1 (0.41) | SIGMAR1GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL13967928 | 0.69 | KDM4E (0.32) | SIGMAR1MAPTKDM4EGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7790781-B2 | Condensation-crosslinkable dental material hardening to dimensionally stable casts | KETTENBACH GMBH & CO. KG (DE) | 2010-09-07 | — | — | US | disclosed |
| US-7790781-B2 | Condensation-crosslinkable dental material hardening to dimensionally stable casts | KETTENBACH GMBH & CO. KG (DE) | 2010-09-07 | — | — | US | disclosed |
| US-20070004821-A1 | Condensation-crosslinked dental material hardening to dimensionally stable casts | KETTENBACH GMBH & CO. KG | 2007-01-04 | — | — | US | disclosed |
| US-20070004821-A1 | Condensation-crosslinked dental material hardening to dimensionally stable casts | KETTENBACH GMBH & CO. KG | 2007-01-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070004821-A1 | Condensation-crosslinked dental material hardening to dimensionally stable casts | SMCHD1, SMC1A, SMC2 | SIGMAR1 3417/4885GRIN2D 271/4885GRIN3B 979/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.