SCHEMBL16376398

SCHEMBL16376398

c1ccc(-c2ccc(-c3ccc(-c4ccc5c6c(cccc46)Oc4ccccc4-5)c4ccccc34)c3ccccc23)cc1

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPK1 P28482 3/20 0.55
KDM4E B2RXH2 2/20 0.55
ATM Q13315 2/20 0.55
METAP2 P50579 1/20 0.38
MEN1 O00255 1/20 0.37
POLB P06746 1/20 0.37
KMT2A Q03164 1/20 0.37
CRHBP P24387 1/20 0.35
CRHR2 Q13324 1/20 0.35
KEAP1 Q14145 1/20 0.35
NFE2L2 Q16236 1/20 0.35
TYMS P04818 3/20 0.34
LIMK1 P53667 2/20 0.34
CLK4 Q9HAZ1 2/20 0.34
PLK4 O00444 1/20 0.34
MAPK9 P45984 1/20 0.34
AKT3 Q9Y243 1/20 0.34
TNF P01375 1/20 0.34
MAP4K4 O95819 1/20 0.33
CSF1R P07333 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16376395 0.98 MAPK1 (0.53) MAPK1KDM4EATMMETAP2MEN1
SCHEMBL18645079 0.93 MAPK1 (0.55) MAPK1KDM4EATMMETAP2MEN1
SCHEMBL16558465 0.93 MAPK1 (0.55) MAPK1KDM4EATMMETAP2MEN1
SCHEMBL16376378 0.92 KDM4E (0.50) MAPK1KDM4EATMMETAP2MEN1
SCHEMBL24923099 0.91 MAPK1 (0.54) MAPK1KDM4EATMMETAP2MEN1
SCHEMBL16558427 0.91 MAPK1 (0.64) MAPK1KDM4EATMMEN1POLB
SCHEMBL16558431 0.91 MAPK1 (0.64) MAPK1KDM4EATMMEN1POLB
SCHEMBL16558442 0.91 MAPK1 (0.64) MAPK1KDM4EATMMEN1POLB
SCHEMBL16558430 0.91 MAPK1 (0.64) MAPK1KDM4EATMMEN1POLB
SCHEMBL16558302 0.91 MAPK1 (0.64) MAPK1KDM4EATMMEN1POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10256416-B2 Compound and organic light-emitting device including the same SAMSUNG DISPLAY CO., LTD. (KR) 2019-04-09 US disclosed
US-20150001479-A1 COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2015-01-01 US disclosed
US-20150001479-A1 COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2015-01-01 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10256416-B2 Compound and organic light-emitting device including the same ALDH1A2, AOX1, OR10J3 MAPK1 617/4885KDM4E 2779/4885ATM 3093/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.