Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 4/20 | 0.51 |
| ▸ | KDR | P35968 | 8/20 | 0.38 |
| ▸ | CNR1 | P21554 | 2/20 | 0.38 |
| ▸ | CNR2 | P34972 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | FLT1 | P17948 | 3/20 | 0.37 |
| ▸ | FLT4 | P35916 | 3/20 | 0.37 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.37 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.36 |
| ▸ | RARB | P10826 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10035810 | 0.82 | HSD11B1 (0.60) | HSD11B1KDRPDE4B | |
| SCHEMBL1316463 | 0.81 | KDR (0.52) | KDRFLT1FLT4 | |
| SCHEMBL29070232 | 0.80 | KDR (0.51) | KDRFLT1FLT4 | |
| SCHEMBL29877358 | 0.80 | KDR (0.51) | KDRFLT1FLT4 | |
| SCHEMBL28848948 | 0.80 | KDR (0.51) | KDRFLT1FLT4 | |
| SCHEMBL29788366 | 0.80 | KDR (0.51) | KDRFLT1FLT4 | |
| SCHEMBL3815157 | 0.78 | KDR (0.46) | KDRFLT1FLT4 | |
| SCHEMBL16377109 | 0.78 | LPL (0.33) | HSD11B1KDR | |
| SCHEMBL30104217 | 0.77 | KDR (0.45) | KDRFLT1FLT4 | |
| SCHEMBL30104214 | 0.77 | KDR (0.45) | KDRFLT1FLT4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150001509-A1 | COMPOSITION | CAMBRIDGE DISPLAY TECHNOLOGY, LTD (GB) | 2015-01-01 | — | — | US | disclosed |