Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | AURKA | O14965 | 1/20 | 0.34 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.34 |
| ▸ | GPR88 | Q9GZN0 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.32 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.32 |
| ▸ | ACP3 | P15309 | 1/20 | 0.32 |
| ▸ | KAT2B | Q92831 | 2/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.31 |
| ▸ | HRH1 | P35367 | 1/20 | 0.30 |
| ▸ | MTOR | P42345 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13460409 | 0.81 | L3MBTL1 (0.43) | L3MBTL1GAAAURKARPS6KB1GPR88 | |
| SCHEMBL15382014 | 0.80 | LMNA (0.47) | L3MBTL1GAATAAR1RAB9A | |
| SCHEMBL16746745 | 0.80 | LMNA (0.47) | L3MBTL1GAATAAR1RAB9A | |
| SCHEMBL15382015 | 0.80 | LMNA (0.47) | L3MBTL1GAATAAR1RAB9A | |
| SCHEMBL13516801 | 0.76 | SCN4A (0.41) | L3MBTL1GAAAURKARPS6KB1HTR2A | |
| SCHEMBL18434877 | 0.76 | TAAR1 (0.47) | L3MBTL1GAAGPR88HTR2ATAAR1 | |
| SCHEMBL18321195 | 0.76 | GAA (0.41) | L3MBTL1GAAAURKARPS6KB1GPR88 | |
| SCHEMBL13438025 | 0.76 | TAAR1 (0.47) | L3MBTL1GAAGPR88HTR2ATAAR1 | |
| SCHEMBL27702036 | 0.76 | SCN4A (0.41) | L3MBTL1GAAAURKARPS6KB1HTR2A | |
| Hydrochloric Acid SCHEMBL23112327 | 0.74 | SCN4A (0.40) | L3MBTL1GAAAURKARPS6KB1HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015002915-A1 | TRICYCLIC PYRI DO-CARBOXAM I D E DERIVATIVES AS ROCK INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2015-01-08 | — | — | WO | disclosed |