SCHEMBL1637895

SCHEMBL1637895

CO[Si](C)(C)c1cc2ccccc2c([Si](C)(C)OC)c1[Si](C)(C)OC

nearest known ligand 0.33

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.33
CYP1A2 P05177 4/20 0.33
KDM4E B2RXH2 3/20 0.33
HIF1A Q16665 2/20 0.33
CYP2A6 P11509 2/20 0.33
NQO1 P15559 1/20 0.33
CYP1B1 Q16678 1/20 0.33
HSD17B10 Q99714 1/20 0.33
HPGD P15428 3/20 0.33
MAPT P10636 2/20 0.33
SMN1; SMN2 Q16637 2/20 0.33
CASP3 P42574 1/20 0.33
SENP7 Q9BQF6 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
POLB P06746 1/20 0.32
CYP2C19 P33261 1/20 0.31
PTGES O14684 1/20 0.31
ALOX5 P09917 1/20 0.31
NPSR1 Q6W5P4 1/20 0.31
ERN1 O75460 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6746717 0.79 NQO1 (0.41) ALDH1A1CYP1A2KDM4EHIF1ACYP2A6
SCHEMBL1638822 0.75 ERN1 (0.34) ALDH1A1CYP1A2KDM4EHIF1ACYP2A6
SCHEMBL27752413 0.73 ALDH1A1 (0.38) ALDH1A1CYP1A2KDM4EHIF1ACYP2A6
SCHEMBL15067824 0.73 CYP2A6 (0.41) ALDH1A1CYP1A2KDM4ECYP2A6HSD17B10
SCHEMBL1640203 0.73 POLB (0.37) ALDH1A1CYP1A2KDM4EHIF1ACYP2A6
SCHEMBL6744734 0.71 NQO1 (0.41) ALDH1A1CYP1A2KDM4EHIF1ACYP2A6
SCHEMBL29417586 0.71 POLB (0.42) ALDH1A1CYP1A2KDM4EHIF1ACYP2A6
SCHEMBL12275391 0.71 ALDH1A1 (0.39) ALDH1A1CYP1A2KDM4EHIF1ACYP2A6
SCHEMBL2346357 0.71 POLB (0.42) ALDH1A1CYP1A2KDM4EHIF1ACYP2A6
SCHEMBL26268819 0.70 TRPM4 (0.41) ALDH1A1CYP1A2KDM4EHIF1ACYP2A6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1391476-B1 PHOTOREACTIVE COMPOSITION SEKISUI CHEMICAL CO LTD (JP) 2015-12-09 EP disclosed
US-8536242-B2 Photocurable composition SEKISUI CHEMICAL CO., LTD. (JP) 2013-09-17 US disclosed
US-20110097669-A1 PHOTOCURABLE COMPOSITION SEKISUI CHEMICAL CO., LTD. (JP) 2011-04-28 US disclosed
US-7312013-B2 Photoreactive composition SEKISUI CHEMICAL CO., LTD. (JP) 2007-12-25 US disclosed
US-20040202956-A1 a photocurable mixture of a hydrolyzable metal (silyl) compound and a reaction, polymerization or crosslinking promoter; curing; adhesives, seals, semiconductors, dielectrics, microlenses, optical fibers, color filters, gas permeable films SEKISUI CHEMICAL CO., LTD. (JP) 2004-10-14 US disclosed
EP-1391476-A1 PHOTOREACTIVE COMPOSITION SEKISUI CHEMICAL CO., LTD. (JP) 2004-02-25 EP disclosed