SCHEMBL1640203

SCHEMBL1640203

CO[Si](OC)(OC)c1cc2ccccc2c([Si](OC)(OC)OC)c1[Si](OC)(OC)OC

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
POLB P06746 1/20 0.37
ALDH1A1 P00352 5/20 0.35
KDM4E B2RXH2 3/20 0.35
MAPK1 P28482 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.35
HPGD P15428 2/20 0.35
NPSR1 Q6W5P4 1/20 0.35
ERN1 O75460 1/20 0.35
HIF1A Q16665 1/20 0.34
CYP1B1 Q16678 1/20 0.34
HSD17B10 Q99714 1/20 0.34
CYP1A2 P05177 3/20 0.34
CYP2A6 P11509 2/20 0.34
NQO1 P15559 1/20 0.34
TUBB4A P04350 1/20 0.33
TUBB P07437 1/20 0.33
TUBA3C P0DPH7 1/20 0.33
TUBA1B P68363 1/20 0.33
TUBA4A P68366 1/20 0.33
TUBB4B P68371 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2346357 0.84 POLB (0.42) POLBALDH1A1KDM4EMAPK1SMN1; SMN2
SCHEMBL29417586 0.84 POLB (0.42) POLBALDH1A1KDM4EMAPK1SMN1; SMN2
SCHEMBL1615832 0.81 TRPM4 (0.42) POLBALDH1A1KDM4EMAPK1SMN1; SMN2
SCHEMBL1638787 0.79 MAPT (0.41) POLBALDH1A1KDM4EMAPK1SMN1; SMN2
SCHEMBL6751520 0.78 NQO1 (0.42) POLBALDH1A1KDM4EMAPK1SMN1; SMN2
SCHEMBL1639907 0.77 NR1I2 (0.33) ALDH1A1KDM4EMAPK1HPGDHIF1A
SCHEMBL17373047 0.75 NQO1 (0.40) POLBALDH1A1KDM4EHPGDERN1
SCHEMBL1637895 0.73 ALDH1A1 (0.33) POLBALDH1A1KDM4ESMN1; SMN2HPGD
SCHEMBL1638822 0.73 ERN1 (0.34) POLBALDH1A1KDM4ESMN1; SMN2HPGD
SCHEMBL3355463 0.73 KDM4E (0.50) POLBALDH1A1KDM4EMAPK1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1391476-B1 PHOTOREACTIVE COMPOSITION SEKISUI CHEMICAL CO LTD (JP) 2015-12-09 EP disclosed
US-8536242-B2 Photocurable composition SEKISUI CHEMICAL CO., LTD. (JP) 2013-09-17 US disclosed
US-20110097669-A1 PHOTOCURABLE COMPOSITION SEKISUI CHEMICAL CO., LTD. (JP) 2011-04-28 US disclosed
US-7312013-B2 Photoreactive composition SEKISUI CHEMICAL CO., LTD. (JP) 2007-12-25 US disclosed
US-20040202956-A1 a photocurable mixture of a hydrolyzable metal (silyl) compound and a reaction, polymerization or crosslinking promoter; curing; adhesives, seals, semiconductors, dielectrics, microlenses, optical fibers, color filters, gas permeable films SEKISUI CHEMICAL CO., LTD. (JP) 2004-10-14 US disclosed
EP-1391476-A1 PHOTOREACTIVE COMPOSITION SEKISUI CHEMICAL CO., LTD. (JP) 2004-02-25 EP disclosed