SCHEMBL16379481

SCHEMBL16379481

C=CC(=O)OCCCCOC(=O)Oc1ccc(C(=O)Oc2ccc(OC(=O)/C=C/c3ccc(OC)cc3)cc2)cc1

nearest known ligand 0.51

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
LMNA P02545 4/20 0.51
SMN1; SMN2 Q16637 1/20 0.51
TDP1 Q9NUW8 2/20 0.48
MAPT P10636 5/20 0.47
KDM4E B2RXH2 1/20 0.47
MAPK1 P28482 1/20 0.46
KMT2A Q03164 4/20 0.46
MEN1 O00255 3/20 0.46
GFER P55789 1/20 0.46
NPC1 O15118 1/20 0.46
F3 P13726 1/20 0.44
GSK3B P49841 1/20 0.42
BCHE P06276 1/20 0.42
MAOB P27338 1/20 0.41
CA12 O43570 1/20 0.41
CA1 P00915 1/20 0.41
CA2 P00918 1/20 0.41
CA4 P22748 1/20 0.41
CA9 Q16790 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8155177 0.94 LMNA (0.58) LMNASMN1; SMN2TDP1MAPTKDM4E
SCHEMBL16379485 0.93 LMNA (0.52) LMNASMN1; SMN2TDP1MAPTKDM4E
SCHEMBL16379457 0.92 LMNA (0.51) LMNASMN1; SMN2TDP1MAPTKDM4E
SCHEMBL18200266 0.92 LMNA (0.51) LMNASMN1; SMN2TDP1MAPTKDM4E
SCHEMBL16379466 0.92 LMNA (0.51) LMNASMN1; SMN2TDP1MAPTKDM4E
SCHEMBL13997902 0.91 MAPT (0.47) LMNASMN1; SMN2MAPTKDM4EKMT2A
SCHEMBL16379502 0.91 MAPT (0.47) LMNASMN1; SMN2MAPTKDM4EKMT2A
SCHEMBL13701170 0.91 MAPT (0.47) LMNASMN1; SMN2MAPTKDM4EKMT2A
SCHEMBL16379464 0.91 LMNA (0.52) LMNASMN1; SMN2TDP1MAPTKDM4E
SCHEMBL13997896 0.90 ALDH1A1 (0.46) LMNASMN1; SMN2MAPTKDM4EKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20150344782-A1 POLYMERIZABLE LIQUID CRYSTAL COMPOUND, LIQUID CRYSTAL COMPOSITION, POLYMER MATERIAL AND METHOD FOR MANUFACTURING THE SAME, AND FILM FUJIFILM CORPORATION (JP) 2015-12-03 US disclosed
US-20150344782-A1 POLYMERIZABLE LIQUID CRYSTAL COMPOUND, LIQUID CRYSTAL COMPOSITION, POLYMER MATERIAL AND METHOD FOR MANUFACTURING THE SAME, AND FILM FUJIFILM CORPORATION (JP) 2015-12-03 US disclosed
US-20150191651-A1 POLYMERIZABLE LIQUID CRYSTAL COMPOUND, LIQUID CRYSTAL COMPOSITION, POLYMER MATERIAL AND METHOD FOR MANUFACTURING THE SAME, AND FILM FUJIFILM CORPORATION (JP) 2015-07-09 US disclosed
US-20150191651-A1 POLYMERIZABLE LIQUID CRYSTAL COMPOUND, LIQUID CRYSTAL COMPOSITION, POLYMER MATERIAL AND METHOD FOR MANUFACTURING THE SAME, AND FILM FUJIFILM CORPORATION (JP) 2015-07-09 US disclosed
US-20150002789-A1 OPTICALLY-COMPENSATORY FILM, POLARIZING PLATE, LIQUID CRYSTAL DISPLAY, AND METHOD OF PRODUCING OPTICALLY-COMPENSATORY FILM FUJIFILM CORPORATION (JP) 2015-01-01 US disclosed
US-20150002789-A1 OPTICALLY-COMPENSATORY FILM, POLARIZING PLATE, LIQUID CRYSTAL DISPLAY, AND METHOD OF PRODUCING OPTICALLY-COMPENSATORY FILM FUJIFILM CORPORATION (JP) 2015-01-01 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150191651-A1 POLYMERIZABLE LIQUID CRYSTAL COMPOUND, LIQUID CRYSTAL COMPOSITION, POLYMER MATERIAL AND METHOD FOR MANUFACTURING THE SAME, AND FILM PYM1, C9, LANCL2 LMNA 210/4885SMN1; SMN2 2516/4885TDP1 4329/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.