SCHEMBL1638013

SCHEMBL1638013

NC1=CC=C2C=CC=CN2C1

nearest known ligand 0.30

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.30
MEN1 O00255 1/20 0.30
ALDH1A1 P00352 1/20 0.30
MAPT P10636 1/20 0.30
HPGD P15428 1/20 0.30
CASP1 P29466 1/20 0.30
CASP7 P55210 1/20 0.30
KMT2A Q03164 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17261368 0.75 KDM4E (0.30) KDM4EMEN1ALDH1A1MAPTHPGD
SCHEMBL4552679 0.75 KDM4E (0.30) KDM4EMEN1ALDH1A1MAPTHPGD
SCHEMBL7604374 0.75 KDM4E (0.33) KDM4EMEN1ALDH1A1MAPTHPGD
Hydrochloric Acid SCHEMBL28174881 0.73 KDM4E (0.33) KDM4EMEN1ALDH1A1MAPTHPGD
SCHEMBL1766246 0.72
Hydrochloric Acid SCHEMBL16961416 0.71
SCHEMBL27258731 0.71 KDM4E (0.31) KDM4EMEN1ALDH1A1MAPTHPGD
SCHEMBL28021022 0.71 KDM4E (0.31) KDM4EMEN1ALDH1A1MAPTHPGD
SCHEMBL27538254 0.71
SCHEMBL168677 0.70

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8536242-B2 Photocurable composition SEKISUI CHEMICAL CO., LTD. (JP) 2013-09-17 US disclosed
US-20110097669-A1 PHOTOCURABLE COMPOSITION SEKISUI CHEMICAL CO., LTD. (JP) 2011-04-28 US disclosed
WO-1996017630-A9 SUBSTITUTED BENZAMIDES AND RADIOLIGAND ANALOGS AND METHODS OF USE 1996-08-08 WO disclosed
WO-1996017630-A1 SUBSTITUTED BENZAMIDES AND RADIOLIGAND ANALOGS AND METHODS OF USE VANDERBILT UNIVERSITY (US) 1996-06-13 WO disclosed
US-5198418-A Substituted alkylamides of teicoplanin compounds GRUPPO LEPETIT S.P.A. (IT) 1993-03-30 US disclosed
EP-0340245-B1 SUBSTITUTED ALKYLAMIDES OF TEICOPLANIN COMPOUNDS GRUPPO LEPETIT S.p.A. (IT) 1992-08-19 EP disclosed
EP-0340245-A1 SUBSTITUTED ALKYLAMIDES OF TEICOPLANIN COMPOUNDS. LEPETIT SPA (IT) 1989-11-08 EP disclosed
WO-1988006600-A1 SUBSTITUTED ALKYLAMIDES OF TEICOPLANIN COMPOUNDS GRUPPO LEPETIT S.P.A. (IT) 1988-09-07 WO disclosed