Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | CASP1 | P29466 | 1/20 | 0.31 |
| ▸ | CASP7 | P55210 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1008141 | 0.87 | KDM4E (0.30) | KDM4EMEN1ALDH1A1MAPTHPGD | |
| SCHEMBL1766246 | 0.86 | — | — | |
| Water SCHEMBL28122664 | 0.86 | KDM4E (0.33) | KDM4EMEN1ALDH1A1MAPTHPGD | |
| Water SCHEMBL28122070 | 0.86 | KDM4E (0.33) | KDM4EMEN1ALDH1A1MAPTHPGD | |
| Hydrochloric Acid SCHEMBL16961416 | 0.84 | — | — | |
| SCHEMBL17261445 | 0.83 | HDAC4 (0.33) | — | |
| SCHEMBL28122665 | 0.82 | CHRM3 (0.37) | — | |
| Water SCHEMBL28838534 | 0.80 | CHRM3 (0.36) | — | |
| Hydrochloric Acid SCHEMBL30571057 | 0.80 | CHRM3 (0.36) | — | |
| SCHEMBL7604374 | 0.75 | KDM4E (0.33) | KDM4EMEN1ALDH1A1MAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104628745-B | A kind of fumarate of rifamycin quinolizine ketone dual-target molecule and preparation method thereof | 丹诺医药(苏州）有限公司 | 2017-03-08 | — | — | CN | claimed |
| CN-104628745-A | Fumarate of rifamycin-quinolizidone dual-target molecule and preparation method thereof | TENNOR THERAPEUTICS LTD | 2015-05-20 | — | — | CN | claimed |
| CN-106029628-B | The preparation method of multifunctional (methyl) acrylate | 东亚合成株式会社 | 2019-09-13 | — | — | CN | disclosed |
| CN-107922555-A | Curing composition | 东亚合成株式会社 | 2018-04-17 | — | — | CN | disclosed |
| CN-107709376-A | Curing composition | 东亚合成株式会社 | 2018-02-16 | — | — | CN | disclosed |
| CN-107709377-A | Curing composition | 东亚合成株式会社 | 2018-02-16 | — | — | CN | disclosed |
| CN-106029628-A | Multifunctional (meth)acrylate manufacturing method | 东亚合成株式会社 | 2016-10-12 | — | — | CN | disclosed |