SCHEMBL7604374

SCHEMBL7604374

OC1=CC=C2C=CC=CN2C1

nearest known ligand 0.33

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 2/20 0.33
ALDH1A1 P00352 2/20 0.33
HPGD P15428 2/20 0.33
MEN1 O00255 1/20 0.33
MAPT P10636 1/20 0.33
CASP1 P29466 1/20 0.33
CASP7 P55210 1/20 0.33
KMT2A Q03164 1/20 0.33
POLB P06746 1/20 0.30
HSD17B10 Q99714 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL28174881 0.98 KDM4E (0.33) KDM4EALDH1A1HPGDMEN1MAPT
SCHEMBL1638013 0.75 KDM4E (0.30) KDM4EALDH1A1HPGDMEN1MAPT
SCHEMBL17261368 0.75 KDM4E (0.30) KDM4EALDH1A1HPGDMEN1MAPT
SCHEMBL4552679 0.75 KDM4E (0.30) KDM4EALDH1A1HPGDMEN1MAPT
SCHEMBL28021022 0.75 KDM4E (0.31) KDM4EALDH1A1HPGDMEN1MAPT
SCHEMBL1766246 0.72
Water SCHEMBL28122070 0.72 KDM4E (0.33) KDM4EALDH1A1HPGDMEN1MAPT
Water SCHEMBL28122664 0.72 KDM4E (0.33) KDM4EALDH1A1HPGDMEN1MAPT
Hydrochloric Acid SCHEMBL16961416 0.71
SCHEMBL27258731 0.71 KDM4E (0.31) KDM4EALDH1A1HPGDMEN1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1265485-A1 USE OF PIPERIDINE BENZODERIVATIVES AS FUNGICIDES Leis, Michelangelo (IT) 2002-12-18 EP disclosed
WO-2001062089-A1 USE OF PIPERIDINE BENZODERIVATIVES AS FUNGICIDES LEIS MICHELANGELO (IT) 2001-08-30 WO disclosed