Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | EPOR | P19235 | 3/20 | 0.46 |
| ▸ | TLR2 | O60603 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | TACR2 | P21452 | 4/20 | 0.42 |
| ▸ | NPY1R | P25929 | 3/20 | 0.41 |
| ▸ | CHRNA1 | P02708 | 2/20 | 0.41 |
| ▸ | CHRNG | P07510 | 2/20 | 0.41 |
| ▸ | CHRNB1 | P11230 | 2/20 | 0.41 |
| ▸ | CHRND | Q07001 | 2/20 | 0.41 |
| ▸ | NPY4R | P50391 | 1/20 | 0.40 |
| ▸ | MME | P08473 | 1/20 | 0.39 |
| ▸ | ECE1 | P42892 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17381391 | 0.86 | CTSS (0.45) | SMN1; SMN2HTTEPORTLR2LMNA | |
| SCHEMBL16384896 | 0.85 | SMN1; SMN2 (0.59) | SMN1; SMN2TLR2LMNAMMEECE1 | |
| SCHEMBL21422694 | 0.85 | SMN1; SMN2 (0.59) | SMN1; SMN2TLR2LMNAMMEECE1 | |
| SCHEMBL16384882 | 0.81 | ALB (0.40) | SMN1; SMN2HTTEPORNPY1RCHRNA1 | |
| SCHEMBL21422716 | 0.79 | SMN1; SMN2 (0.53) | SMN1; SMN2TLR2LMNAMMEECE1 | |
| SCHEMBL16371656 | 0.77 | MEN1 (0.40) | SMN1; SMN2TLR2TACR2NPY1RNPY4R | |
| SCHEMBL17381478 | 0.73 | SMN1; SMN2 (0.57) | SMN1; SMN2LMNA | |
| SCHEMBL17804046 | 0.73 | SMN1; SMN2 (0.65) | SMN1; SMN2MMEECE1 | |
| SCHEMBL16384724 | 0.73 | SMN1; SMN2 (0.54) | SMN1; SMN2LMNAMMEECE1 | |
| SCHEMBL27500556 | 0.72 | FOLH1 (0.48) | HTTMMEECE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015006728-A2 | SITE-SPECIFIC CHEMOENZYMATIC PROTEIN MODIFICATIONS | USERA AIMEE (US) | 2015-01-15 | — | — | WO | disclosed |