Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 4/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | IDO1 | P14902 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | CTSK | P43235 | 2/20 | 0.42 |
| ▸ | BCHE | P06276 | 1/20 | 0.41 |
| ▸ | CNR2 | P34972 | 1/20 | 0.41 |
| ▸ | CTSL | P07711 | 1/20 | 0.41 |
| ▸ | CTSB | P07858 | 1/20 | 0.41 |
| ▸ | AKT1 | P31749 | 1/20 | 0.41 |
| ▸ | SYK | P43405 | 1/20 | 0.40 |
| ▸ | PPARA | Q07869 | 1/20 | 0.40 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.40 |
| ▸ | HTR1A | P08908 | 1/20 | 0.40 |
| ▸ | TLR2 | O60603 | 1/20 | 0.40 |
| ▸ | EPOR | P19235 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | REN | P00797 | 1/20 | 0.38 |
| ▸ | SUCNR1 | Q9BXA5 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17381478 | 0.88 | SMN1; SMN2 (0.57) | CTSSSMN1; SMN2LMNACTSKBCHE | |
| SCHEMBL16384887 | 0.86 | SMN1; SMN2 (0.48) | SMN1; SMN2LMNAHTTTLR2EPOR | |
| SCHEMBL22857443 | 0.85 | CTSS (0.46) | CTSSSMN1; SMN2IDO1CTSKCTSL | |
| SCHEMBL25132765 | 0.77 | SYK (0.49) | CTSSSMN1; SMN2LMNACTSKBCHE | |
| SCHEMBL31365850 | 0.76 | LMNA (0.51) | CTSSSMN1; SMN2LMNACTSKBCHE | |
| SCHEMBL16384882 | 0.76 | ALB (0.40) | SMN1; SMN2HTTEPOR | |
| SCHEMBL12196470 | 0.76 | SMN1; SMN2 (0.76) | CTSSSMN1; SMN2LMNAIDO1HTT | |
| SCHEMBL19726709 | 0.76 | LMNA (0.55) | CTSSSMN1; SMN2LMNAIDO1CTSK | |
| SCHEMBL12196508 | 0.76 | MAPT (0.58) | SMN1; SMN2LMNAMAPT | |
| SCHEMBL30859205 | 0.76 | MAPT (0.58) | SMN1; SMN2LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015200078-A1 | FATTY ACIDS AND THEIR USE IN CONJUGATION TO BIOMOLECULES | NOVARTIS AG (CH) | 2015-12-30 | — | — | WO | disclosed |