Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.43 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.43 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.42 |
| ▸ | HTR6 | P50406 | 5/20 | 0.42 |
| ▸ | PTGDR2 | Q9Y5Y4 | 3/20 | 0.42 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | SGMS2 | Q8NHU3 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | HTR1A | P08908 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16385182 | 0.89 | SLC22A12 (0.44) | SLC22A12HTR6PTGDR2MRGPRX4ALDH1A1 | |
| SCHEMBL17788251 | 0.87 | MRGPRX4 (0.41) | SLC22A12HTR6PTGDR2MRGPRX4ALDH1A1 | |
| SCHEMBL17788242 | 0.86 | SLC22A12 (0.40) | SLC22A12HTR6PTGDR2MRGPRX4ALDH1A1 | |
| SCHEMBL17788255 | 0.84 | NR1H4 (0.41) | SLC22A12HTR6MRGPRX4ALDH1A1 | |
| SCHEMBL17788243 | 0.82 | MRGPRX4 (0.46) | FFAR4HTR6PTGDR2MRGPRX4ALDH1A1 | |
| SCHEMBL16385418 | 0.81 | HTR6 (0.46) | FFAR4FFAR1SLC22A12HTR6PTGDR2 | |
| SCHEMBL20195631 | 0.80 | SSTR4 (0.41) | SGMS2CYP1A2CYP2C19SLC6A2SLC6A4 | |
| SCHEMBL20195491 | 0.79 | SSTR4 (0.40) | SLC22A12SLC6A4HTR1A | |
| SCHEMBL16385179 | 0.78 | PTGDR2 (0.44) | SLC22A12HTR6PTGDR2MRGPRX4ALDH1A1 | |
| SCHEMBL17788259 | 0.78 | MRGPRX4 (0.40) | HTR6PTGDR2MRGPRX4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015005499-A1 | TETRAZOLINONE COMPOUND AND USE THEREOF | 住友化学株式会社 (JP) | 2015-01-15 | — | — | WO | disclosed |