Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SSTR4 | P31391 | 4/20 | 0.40 |
| ▸ | CNR2 | P34972 | 3/20 | 0.35 |
| ▸ | CNR1 | P21554 | 1/20 | 0.35 |
| ▸ | PDK2 | Q15119 | 2/20 | 0.34 |
| ▸ | PDK4 | Q16654 | 2/20 | 0.34 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.34 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.34 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.34 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.34 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.34 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.34 |
| ▸ | BDKRB1 | P46663 | 1/20 | 0.34 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.32 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.32 |
| ▸ | HTR1A | P08908 | 1/20 | 0.32 |
| ▸ | HTR1D | P28221 | 1/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
| ▸ | PPARG | P37231 | 1/20 | 0.32 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20195498 | 0.85 | SSTR4 (0.41) | SSTR4CNR2CNR1HTR1ASLC6A4 | |
| SCHEMBL20195502 | 0.84 | GABRA5 (0.40) | SSTR4PDK2PDK4GABRA5 | |
| SCHEMBL20195479 | 0.82 | KMT2A (0.38) | — | |
| SCHEMBL16384993 | 0.79 | FFAR4 (0.43) | SLC22A12HTR1ASLC6A4 | |
| SCHEMBL16385182 | 0.79 | SLC22A12 (0.44) | SLC22A12PPARG | |
| SCHEMBL20195657 | 0.79 | P2RX7 (0.36) | SSTR4CNR2KCNH2P2RX7 | |
| SCHEMBL17788242 | 0.78 | SLC22A12 (0.40) | PDK2PDK4SLC22A12 | |
| SCHEMBL20195658 | 0.78 | ALDH1A1 (0.40) | SSTR4PDK2PDK4GABRA1GABRG2 | |
| SCHEMBL20195558 | 0.77 | SSTR4 (0.37) | SSTR4CNR2CNR1PDK2PDK4 | |
| SCHEMBL20195631 | 0.76 | SSTR4 (0.41) | SSTR4HTR1ASLC6A4P2RX7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3029035-B1 | TETRAZOLINONE COMPOUND, AND USE THEREOF | SUMITOMO CHEMICAL CO (JP) | 2018-05-30 | — | — | EP | disclosed |