Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.37 |
| ▸ | PRKCG | P05129 | 1/20 | 0.37 |
| ▸ | PRKCB | P05771 | 1/20 | 0.37 |
| ▸ | PRKCA | P17252 | 1/20 | 0.37 |
| ▸ | PRKCH | P24723 | 1/20 | 0.37 |
| ▸ | PRKCI | P41743 | 1/20 | 0.37 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.37 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.37 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.37 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.37 |
| ▸ | PRKD1 | Q15139 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | LPAR5 | Q9H1C0 | 4/20 | 0.36 |
| ▸ | LPAR6 | P43657 | 3/20 | 0.36 |
| ▸ | LPAR1 | Q92633 | 3/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8223606 | 0.81 | USP2 (0.37) | USP2TSHRSPHK1HTTPRKD3 | |
| SCHEMBL8232147 | 0.81 | USP2 (0.50) | USP2TSHRSPHK1HTTHSD17B10 | |
| SCHEMBL11991414 | 0.79 | HSD17B10 (0.56) | USP2SPHK1HTTHSD17B10 | |
| SCHEMBL814746 | 0.78 | PIK3CD (0.31) | — | |
| SCHEMBL15780013 | 0.77 | TSHR (0.41) | USP2TSHRSPHK1HTTPRKD3 | |
| SCHEMBL8987536 | 0.77 | TSHR (0.41) | USP2TSHRSPHK1HTTPRKD3 | |
| SCHEMBL16004035 | 0.77 | TSHR (0.41) | USP2TSHRSPHK1HTTPRKD3 | |
| Isobutane SCHEMBL3013742 | 0.75 | — | — | |
| SCHEMBL22112913 | 0.75 | CA2 (0.32) | HSD17B10 | |
| SCHEMBL15151965 | 0.75 | TSHR (0.42) | USP2TSHRSPHK1HTTPRKD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150104403-A1 | CATIONIC POLYGLYCERYL COMPOSITIONS AND COMPOUNDS | KENVUE BRANDS LLC | 2015-04-16 | — | — | US | disclosed |
| US-20150104402-A1 | CATIONIC POLYGLYCERYL COMPOSITIONS AND COMPOUNDS | JOHNSON & JOHNSON CONSUMER INC. | 2015-04-16 | — | — | US | disclosed |
| US-20150104401-A1 | CATIONIC POLYGLYCERYL COMPOSITIONS AND COMPOUNDS | JOHNSON & JOHNSON CONSUMER INC. | 2015-04-16 | — | — | US | disclosed |
| US-8986665-B2 | Cationic polyglyceryl compositions and compounds | JOHNSON & JOHNSON CONSUMER COMPANIES, INC. (US) | 2015-03-24 | — | — | US | disclosed |
| US-8961945-B2 | Cationic polyglyceryl compositions and compounds | JOHNSON & JOHNSON CONSUMER COMPANIES, INC. (US) | 2015-02-24 | — | — | US | disclosed |
| US-20140044661-A1 | CATIONIC POLYGLYCERYL COMPOSITIONS AND COMPOUND | JOHNSON & JOHNSON CONSUMER COMPANIES, INC. (US) | 2014-02-13 | — | — | US | disclosed |
| US-20120093753-A1 | CATIONIC POLYGLYCERYL COMPOSITIONS AND COMPOUNDS | JOHNSON & JOHNSON CONSUMER INC. | 2012-04-19 | — | — | US | disclosed |
| US-20120087882-A1 | CATIONIC POLYGLYCERYL COMPOSITIONS AND COMPOUNDS | KENVUE BRANDS LLC | 2012-04-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150104402-A1 | CATIONIC POLYGLYCERYL COMPOSITIONS AND COMPOUNDS | PHOSPHO1, SGMS1, SGMS2 | USP2 2230/4885TSHR 3821/4885SPHK1 368/4885 |
| US-20150104401-A1 | CATIONIC POLYGLYCERYL COMPOSITIONS AND COMPOUNDS | PHOSPHO1, SGMS1, SGMS2 | USP2 2230/4885TSHR 3821/4885SPHK1 368/4885 |
| US-20120093753-A1 | CATIONIC POLYGLYCERYL COMPOSITIONS AND COMPOUNDS | PHOSPHO1, SGMS1, SGMS2 | USP2 2230/4885TSHR 3821/4885SPHK1 368/4885 |
| US-20150104403-A1 | CATIONIC POLYGLYCERYL COMPOSITIONS AND COMPOUNDS | PHOSPHO1, SGMS1, SGMS2 | USP2 2230/4885TSHR 3821/4885SPHK1 368/4885 |
| US-20120087882-A1 | CATIONIC POLYGLYCERYL COMPOSITIONS AND COMPOUNDS | PHOSPHO1, SGMS1, SGMS2 | USP2 2230/4885TSHR 3821/4885SPHK1 368/4885 |
| US-20140044661-A1 | CATIONIC POLYGLYCERYL COMPOSITIONS AND COMPOUND | PHOSPHO1, SGMS1, SGMS2 | USP2 2400/4885TSHR 3927/4885SPHK1 361/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.