Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP1 | P03956 | 1/20 | 0.35 |
| ▸ | MMP8 | P22894 | 1/20 | 0.35 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.35 |
| ▸ | CTSB | P07858 | 1/20 | 0.32 |
| ▸ | METAP2 | P50579 | 1/20 | 0.31 |
| ▸ | GLS | O94925 | 1/20 | 0.31 |
| ▸ | DPP4 | P27487 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15028136 | 0.86 | DPP4 (0.39) | MMP1MMP8ADAM17CTSBMETAP2 | |
| SCHEMBL13285826 | 0.78 | DPP4 (0.41) | MMP1MMP8ADAM17CTSBMETAP2 | |
| SCHEMBL15386492 | 0.78 | DPP4 (0.41) | MMP1MMP8ADAM17CTSBMETAP2 | |
| SCHEMBL19221622 | 0.77 | MMP1 (0.39) | MMP1MMP8ADAM17CTSBMETAP2 | |
| SCHEMBL31074241 | 0.76 | DPP4 (0.41) | MMP1MMP8ADAM17GLSDPP4 | |
| SCHEMBL418389 | 0.73 | MMP1 (0.38) | MMP1MMP8ADAM17GLSDPP4 | |
| SCHEMBL15087472 | 0.72 | DPP4 (0.41) | MMP1MMP8ADAM17GLSDPP4 | |
| Hydrochloric Acid SCHEMBL15618895 | 0.72 | MMP1 (0.38) | MMP1MMP8ADAM17GLSDPP4 | |
| Hydrochloric Acid SCHEMBL15619093 | 0.72 | MMP1 (0.38) | MMP1MMP8ADAM17GLSDPP4 | |
| Hydrochloric Acid SCHEMBL15618898 | 0.72 | MMP1 (0.38) | MMP1MMP8ADAM17GLSDPP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8933056-B2 | Soft protease inhibitors and pro-soft forms thereof | TRUSTEES OF TUFTS COLLEGE (US) | 2015-01-13 | — | — | US | disclosed |