Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP1 | P03956 | 1/20 | 0.39 |
| ▸ | MMP8 | P22894 | 1/20 | 0.39 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.39 |
| ▸ | ARG1 | P05089 | 1/20 | 0.35 |
| ▸ | MMP2 | P08253 | 9/20 | 0.33 |
| ▸ | MMP3 | P08254 | 5/20 | 0.33 |
| ▸ | CTSB | P07858 | 3/20 | 0.33 |
| ▸ | METAP2 | P50579 | 2/20 | 0.33 |
| ▸ | GLS | O94925 | 1/20 | 0.33 |
| ▸ | DPP4 | P27487 | 2/20 | 0.32 |
| ▸ | FAP | Q12884 | 1/20 | 0.32 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.32 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.32 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.32 |
| ▸ | BMP1 | P13497 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15386492 | 0.85 | DPP4 (0.41) | MMP1MMP8ADAM17ARG1MMP2 | |
| SCHEMBL13285826 | 0.85 | DPP4 (0.41) | MMP1MMP8ADAM17ARG1MMP2 | |
| SCHEMBL15028136 | 0.80 | DPP4 (0.39) | MMP1MMP8ADAM17ARG1CTSB | |
| SCHEMBL16388148 | 0.77 | MMP1 (0.35) | MMP1MMP8ADAM17CTSBMETAP2 | |
| SCHEMBL31074241 | 0.76 | DPP4 (0.41) | MMP1MMP8ADAM17MMP2MMP3 | |
| SCHEMBL418389 | 0.73 | MMP1 (0.38) | MMP1MMP8ADAM17MMP2GLS | |
| SCHEMBL15087472 | 0.72 | DPP4 (0.41) | MMP1MMP8ADAM17MMP2GLS | |
| Hydrochloric Acid SCHEMBL15619093 | 0.72 | MMP1 (0.38) | MMP1MMP8ADAM17MMP2GLS | |
| Hydrochloric Acid SCHEMBL15618898 | 0.72 | MMP1 (0.38) | MMP1MMP8ADAM17MMP2GLS | |
| Hydrochloric Acid SCHEMBL15618895 | 0.72 | MMP1 (0.38) | MMP1MMP8ADAM17MMP2GLS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170226155-A1 | Smart Pro-Drugs of Serine Protease Inhibitors | TRUSTEES OF TUFTS COLLEGE (US) | 2017-08-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170226155-A1 | Smart Pro-Drugs of Serine Protease Inhibitors | FAP, PREP, CTSC | MMP1 554/4885MMP8 941/4885ADAM17 59/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.