Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGAM | O43451 | 3/20 | 0.46 |
| ▸ | GAA | P10253 | 3/20 | 0.46 |
| ▸ | SI | P14410 | 3/20 | 0.46 |
| ▸ | MGAM2 | Q2M2H8 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | BCHE | P06276 | 9/20 | 0.43 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.41 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.41 |
| ▸ | HTR1A | P08908 | 1/20 | 0.41 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.41 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.41 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.41 |
| ▸ | ERN1 | O75460 | 1/20 | 0.41 |
| ▸ | RXRA | P19793 | 1/20 | 0.40 |
| ▸ | RXRB | P28702 | 1/20 | 0.40 |
| ▸ | RXRG | P48443 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27894243 | 0.91 | MGAM (0.45) | MGAMGAASIMGAM2KDM4E | |
| SCHEMBL1639404 | 0.88 | MGAM (0.44) | MGAMGAASIMGAM2KDM4E | |
| SCHEMBL1637529 | 0.87 | PTPN5 (0.48) | MGAMGAASIMGAM2KDM4E | |
| SCHEMBL1638077 | 0.86 | MGAM (0.44) | MGAMGAASIMGAM2KDM4E | |
| SCHEMBL1637791 | 0.86 | PTPN5 (0.42) | MGAMGAASIMGAM2KDM4E | |
| SCHEMBL27877417 | 0.85 | MGAM (0.43) | MGAMGAASIMGAM2KDM4E | |
| SCHEMBL12726012 | 0.85 | PTGER1 (0.39) | MGAMGAASIMGAM2L3MBTL1 | |
| SCHEMBL12646975 | 0.84 | KDM4E (0.40) | GAAKDM4EL3MBTL1ADRA1DADRA1A | |
| SCHEMBL1637643 | 0.83 | BCHE (0.43) | MGAMGAASIMGAM2KDM4E | |
| SCHEMBL27864181 | 0.81 | MAOB (0.48) | MGAMGAASIMGAM2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8541521-B2 | Catalyst compounds and use thereof | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2013-09-24 | — | — | US | disclosed |
| US-20110098427-A1 | Catalyst Compounds And Use Thereof | EXXONMOBIL CHEMICAL PATENTS INC. | 2011-04-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110098427-A1 | Catalyst Compounds And Use Thereof | THEM6, OPRM1, NOTUM | MGAM 570/4885GAA 4058/4885SI 4122/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.