Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 3/20 | 0.48 |
| ▸ | MMP2 | P08253 | 2/20 | 0.38 |
| ▸ | MMP9 | P14780 | 1/20 | 0.38 |
| ▸ | TERT | O14746 | 5/20 | 0.37 |
| ▸ | SPHK1 | Q9NYA1 | 4/20 | 0.36 |
| ▸ | SUV39H2 | Q9H5I1 | 2/20 | 0.35 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.33 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.33 |
| ▸ | SPHK2 | Q9NRA0 | 1/20 | 0.33 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13820171 | 0.90 | LTA4H (0.45) | LTA4HMMP2MMP9TERTSPHK1 | |
| Hydrochloric Acid SCHEMBL13717210 | 0.89 | LTA4H (0.44) | LTA4HMMP2MMP9TERTSPHK1 | |
| Hydrochloric Acid SCHEMBL13717208 | 0.89 | LTA4H (0.44) | LTA4HMMP2MMP9TERTSPHK1 | |
| SCHEMBL16389212 | 0.87 | LTA4H (0.45) | LTA4HMMP2MMP9TERTSPHK1 | |
| SCHEMBL13820141 | 0.85 | LTA4H (0.42) | LTA4HMMP2MMP9TERTSPHK1 | |
| SCHEMBL13717225 | 0.83 | LTA4H (0.42) | LTA4HMMP2MMP9TERTSPHK1 | |
| SCHEMBL13717228 | 0.83 | LTA4H (0.42) | LTA4HMMP2MMP9TERTSPHK1 | |
| SCHEMBL13820179 | 0.81 | LTA4H (0.44) | LTA4HMMP2MMP9TERTSUV39H2 | |
| SCHEMBL13820111 | 0.81 | LTA4H (0.44) | LTA4HMMP2MMP9TERTSUV39H2 | |
| SCHEMBL13717004 | 0.81 | RAB9A (0.37) | LTA4H |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8927728-B2 | Dipeptide acetylene conjugates and a method for photocleavage of double strand DNA by dipeptide acetylene conjugates | The Florida State University Research Foundation, Inc. (US) | 2015-01-06 | — | — | US | disclosed |