Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 1/20 | 0.54 |
| ▸ | PELP1 | Q8IZL8 | 1/20 | 0.54 |
| ▸ | EP300 | Q09472 | 1/20 | 0.51 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.51 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.49 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.49 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 4/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | MYC | P01106 | 3/20 | 0.44 |
| ▸ | MAX | P61244 | 3/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17775433 | 0.86 | MYC (0.54) | ARPELP1EP300HIF1AAKR1C3 | |
| SCHEMBL16392496 | 0.86 | AR (0.58) | ARPELP1EP300HIF1AMAPT | |
| SCHEMBL16392534 | 0.86 | EP300 (0.48) | ARPELP1EP300HIF1AMAPT | |
| SCHEMBL17795677 | 0.84 | EP300 (0.53) | ARPELP1EP300HIF1AMAPT | |
| SCHEMBL16392505 | 0.82 | AKR1C3 (0.39) | AKR1C3AKR1C2AKR1C1MAPTKMT2A | |
| SCHEMBL16392556 | 0.80 | EP300 (0.52) | ARPELP1EP300HIF1AMAPT | |
| SCHEMBL16369635 | 0.79 | MYC (0.62) | ARPELP1EP300HIF1AAKR1C3 | |
| SCHEMBL17795676 | 0.79 | EP300 (0.52) | ARPELP1EP300HIF1AMAPT | |
| SCHEMBL12070189 | 0.78 | EP300 (0.65) | ARPELP1EP300HIF1AAKR1C3 | |
| SCHEMBL17795679 | 0.77 | EP300 (0.50) | ARPELP1EP300HIF1AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160145304-A1 | CYSTOBACTAMIDES | HELMHOLTZ-ZENTRUM FUR INFEKTIONSFORSCHUNG GMBH (DE) | 2016-05-26 | — | — | US | disclosed |
| WO-2015003816-A2 | CYSTOBACTAMIDES | Helmholtz-Zentrum für Infektionsforschung GmbH (DE) | 2015-01-15 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160145304-A1 | CYSTOBACTAMIDES | CTH, SLC7A11, CBS | AR 2913/4885PELP1 1614/4885EP300 3526/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.