Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | FGF2 | P09038 | 1/20 | 0.37 |
| ▸ | MDK | P21741 | 1/20 | 0.37 |
| ▸ | PTPN1 | P18031 | 11/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | PTPN2 | P17706 | 2/20 | 0.35 |
| ▸ | PTPN6 | P29350 | 2/20 | 0.35 |
| ▸ | PTPN11 | Q06124 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | TYMP | P19971 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9702258 | 0.86 | PTPN1 (0.39) | KMT2APTPN1POLBPTPN2PTPN6 | |
| SCHEMBL15592304 | 0.85 | LMNA (0.51) | LMNAKMT2APTPN1CYP3A4MAPT | |
| SCHEMBL22855661 | 0.84 | LMNA (0.47) | LMNAKMT2APTPN1CYP3A4MAPT | |
| SCHEMBL24699706 | 0.81 | LMNA (0.44) | LMNAKMT2ACYP3A4MAPTCYP2C9 | |
| SCHEMBL18413388 | 0.80 | LMNA (0.35) | LMNAKMT2AFGF2MDKPTPN1 | |
| SCHEMBL16393094 | 0.80 | LMNA (0.34) | LMNAKMT2AFGF2MDKPTPN1 | |
| SCHEMBL16217825 | 0.79 | LMNA (0.41) | LMNAKMT2ACYP3A4MAPTCYP2C9 | |
| SCHEMBL18349615 | 0.79 | TYMP (0.38) | KMT2ACYP3A4TYMP | |
| SCHEMBL16393010 | 0.79 | PTPN1 (0.47) | LMNAKMT2AMDKPTPN1CYP3A4 | |
| SCHEMBL16392954 | 0.79 | LMNA (0.49) | LMNAKMT2APTPN1CYP3A4MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015006740-A2 | OLIGONUCLEOTIDE-LIGAND CONJUGATES AND PROCESS FOR THEIR PREPARATION | ALNYLAM PHARMACEUTICALS, INC. (US) | 2015-01-15 | — | — | WO | disclosed |