Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | BCHE | P06276 | 3/20 | 0.33 |
| ▸ | ACHE | P22303 | 3/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.33 |
| ▸ | TNF | P01375 | 2/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | GAPDH | P04406 | 1/20 | 0.32 |
| ▸ | FGF2 | P09038 | 1/20 | 0.32 |
| ▸ | MDK | P21741 | 1/20 | 0.32 |
| ▸ | HRAS | P01112 | 1/20 | 0.31 |
| ▸ | PTPN1 | P18031 | 5/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16392920 | 0.92 | LMNA (0.42) | LMNAKMT2ABCHEACHEHDAC6 | |
| SCHEMBL16393095 | 0.91 | LMNA (0.33) | LMNAKMT2ABCHEACHEHDAC6 | |
| SCHEMBL18349846 | 0.87 | BCHE (0.36) | BCHEACHEHDAC6TNF | |
| SCHEMBL16393093 | 0.85 | — | — | |
| SCHEMBL18349597 | 0.82 | BCHE (0.37) | BCHEACHEHDAC6 | |
| SCHEMBL29929081 | 0.80 | LMNA (0.46) | LMNAKMT2ACYP3A4MAPTCYP2C9 | |
| SCHEMBL16393030 | 0.80 | LMNA (0.40) | LMNAKMT2ACYP3A4MAPTCYP2C9 | |
| SCHEMBL18413388 | 0.80 | LMNA (0.35) | LMNAKMT2ACYP3A4MAPTCYP2C9 | |
| SCHEMBL16392921 | 0.78 | LMNA (0.35) | LMNAKMT2ACYP3A4MAPTCYP2C9 | |
| SCHEMBL18349852 | 0.78 | BCHE (0.33) | BCHEACHEHDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015006740-A2 | OLIGONUCLEOTIDE-LIGAND CONJUGATES AND PROCESS FOR THEIR PREPARATION | ALNYLAM PHARMACEUTICALS, INC. (US) | 2015-01-15 | — | — | WO | disclosed |