SCHEMBL16394285

SCHEMBL16394285

Clc1cccc(-c2ccc(-c3cccc(Cl)c3)cc2)c1

nearest known ligand 0.71

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
TAAR1 Q96RJ0 2/20 0.71
ALOX5 P09917 1/20 0.67
MAOB P27338 2/20 0.63
ESR2 Q92731 1/20 0.59
PGR P06401 4/20 0.53
CYP1A2 P05177 1/20 0.52
BACE1 P56817 1/20 0.52
TDP2 O95551 2/20 0.50
JAK2 O60674 1/20 0.50
MAP4K4 O95819 3/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31491189 1.00 TAAR1 (0.71) TAAR1ALOX5MAOBESR2PGR
SCHEMBL20669453 0.97 TAAR1 (0.68) TAAR1ALOX5MAOBESR2PGR
SCHEMBL16394095 0.95 TAAR1 (0.65) TAAR1ALOX5MAOBESR2PGR
SCHEMBL1520884 0.95 TAAR1 (0.65) TAAR1ALOX5MAOBESR2PGR
SCHEMBL29776911 0.95 TAAR1 (0.65) TAAR1ALOX5MAOBESR2PGR
SCHEMBL31222672 0.94 ALOX5 (0.65) TAAR1ALOX5MAOBESR2PGR
SCHEMBL817554 0.94 ALOX5 (0.65) TAAR1ALOX5MAOBESR2PGR
SCHEMBL17725876 0.92 TAAR1 (0.63) TAAR1ALOX5MAOBESR2PGR
SCHEMBL22167038 0.92 TAAR1 (0.63) TAAR1ALOX5MAOBESR2PGR
SCHEMBL18371178 0.92 TAAR1 (0.63) TAAR1ALOX5MAOBESR2PGR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9224958-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2015-12-29 US disclosed
US-9224958-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2015-12-29 US disclosed
US-9224958-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2015-12-29 US disclosed
US-20150021557-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2015-01-22 US disclosed
US-20150021557-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2015-01-22 US disclosed
US-20150021557-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2015-01-22 US disclosed