SCHEMBL817554

SCHEMBL817554

Clc1cccc(-c2cccc(Cl)c2)c1

nearest known ligand 0.65

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 1/20 0.65
TAAR1 Q96RJ0 2/20 0.62
ESR2 Q92731 1/20 0.58
MAOB P27338 2/20 0.56
TSHR P16473 2/20 0.52
ALDH1A1 P00352 1/20 0.52
NOTUM Q6P988 2/20 0.52
NPC1 O15118 1/20 0.52
TP53 P04637 1/20 0.52
NFKB1 P19838 1/20 0.52
RAB9A P51151 1/20 0.52
NFKB2 Q00653 1/20 0.52
RELA Q04206 1/20 0.52
SMN1; SMN2 Q16637 1/20 0.52
IDO1 P14902 4/20 0.50
BACE1 P56817 1/20 0.50
PGR P06401 1/20 0.48
JAK2 O60674 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31222672 1.00 ALOX5 (0.65) ALOX5TAAR1ESR2MAOBTSHR
SCHEMBL29629014 0.97 ALOX5 (0.62) ALOX5TAAR1ESR2MAOBTSHR
Hydrochloric Acid SCHEMBL28332867 0.97 ALOX5 (0.62) ALOX5TAAR1ESR2MAOBTSHR
Hydrochloric Acid SCHEMBL31070804 0.97 ALOX5 (0.62) ALOX5TAAR1ESR2MAOBTSHR
SCHEMBL16394285 0.94 TAAR1 (0.71) ALOX5TAAR1ESR2MAOBBACE1
SCHEMBL31491189 0.94 TAAR1 (0.71) ALOX5TAAR1ESR2MAOBBACE1
SCHEMBL29788033 0.91 TAAR1 (0.61) ALOX5TAAR1ESR2MAOBTSHR
SCHEMBL4453361 0.91 ALOX5 (0.58) ALOX5TAAR1ESR2MAOBTSHR
SCHEMBL20669453 0.91 TAAR1 (0.68) ALOX5TAAR1ESR2MAOBBACE1
SCHEMBL170231 0.91 TAAR1 (0.61) ALOX5TAAR1ESR2MAOBTSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 401 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11981616-B2 Method for preparing 3,3′-diaminobenzidine Hubei Huida High-Tech Co., Ltd (CN) 2024-05-14 US claimed
US-20240109835-A1 METHOD FOR PREPARING 3,3'-DIAMINOBENZIDINE HUBEI HUIDA HIGH-TECH CO., LTD. (CN) 2024-04-04 US claimed
CN-116893235-A Method and kit for determining polychlorinated biphenyl and multi-class brominated flame retardant residues in traditional Chinese medicine 江苏省食品药品监督检验研究院(江苏省食品质量安全监控中心) 2023-10-17 CN claimed
CN-115108918-B Preparation method of 3,3', 4' -tetraminobiphenyl 湖北汇达科技发展有限公司 2023-06-02 CN claimed
CN-115108918-A Preparation method of 3,3',4,4' -tetraaminobiphenyl 北京英力精化技术发展有限公司 2022-09-27 CN claimed
EP-3881907-A1 METHOD FOR DECHLORINATION OF ONE OR MORE AROMATIC ORGANOCHLORINE COMPOUND(S) CONTAINED IN AN OIL OR FORMING SAID OIL - ASSOCIATED ELECTRICAL/ELECTRONIC DEVICE AND INSTALLATION Université de Lille (FR) 2021-09-22 EP claimed
US-7989194-B2 PCB-degrading recombinant bacterium, product for the bioremediation and method of bioremediation UNIVERSIDAD TECNICA FEDERICO SANTA MARIA (CL) 2011-08-02 US claimed
EP-0968739-B1 Method for decomposing halogenated aliphatic and aromatic compounds CANON KK (JP) 2010-06-16 EP claimed
US-20080318302-A1 PCB-Degrading recombinant bacterium, product for the bioremediation and method of bioremediation UNIVERSIDAD TECNICA FEDERICO SANTA MARIA (CL) 2008-12-25 US claimed
EP-1005881-B1 Method and apparatus for decomposing halogenated aliphatic hydrocarbon compounds or aromatic compounds CANON KK (JP) 2005-01-19 EP claimed
US-6794168-B1 USING MONOOXYGENASE ENZYME P450CAM; MAY BE CARRIED OUT IN CELLS, ANIMALS OR PLANTS; FOR REDUCING ENVIRONMENTAL POLLUTION ISIS INNOVATION LIMITED (GB) 2004-09-21 US claimed
US-6616815-B2 Contacting under irradiation with light a medium containing at least one of a halogenated aliphatic hydrocarbon compound and an aromatic compound with functional water produced by electrolysis of water containing an electrolyte CANON KABUSHIKI KAISHA (JP) 2003-09-09 US claimed
US-20030164286-A1 Apparatus for decomposing halogenated aliphatic hydrocarbon compounds or aromatic compounds CANON KABUSHIKI KAISHA (JP) 2003-09-04 US claimed
US-20020163135-A1 METHOD FOR DECOMPOSING HALOGENATED ALIPHATIC HYDROCARBON COMPOUNDS OR AROMATIC COMPOUNDS, METHOD FOR CLEANING MEDIUM CONTAMINATED WITH AT LEAST ONE OF THESE COMPOUNDS, AND APPARATUS FOR THESE CANON KABUSHIKI KAISHA (JP) 2002-11-07 US claimed
US-20020130030-A1 METHOD OF DECOMPOSING HALOGENATED ALIPHATIC HYDROCARBON COMPOUNDS OR AROMATIC COMPOUNDS AND APPARATUS TO BE USED FOR THE SAME AS WELL AS METHOD OF CLARIFYING EXHAUST GAS AND APPARATUS TO BE USED FOR THE SAME CANON KABUSHIKI KAISHA (JP) 2002-09-19 US claimed
EP-1005881-A1 Method and apparatus for decomposing halogenated aliphatic hydrocarbon compounds or aromatic compounds CANON KABUSHIKI KAISHA (JP) 2000-06-07 EP claimed
EP-0968739-A1 Method and apparatus for decomposing halogenated aliphatic and aromatic compounds CANON KABUSHIKI KAISHA (JP) 2000-01-05 EP claimed
EP-4265691-B1 COATING SOLUTION, GLASS SHEET AND LAMINATED GLASS FOR BLOCKING UV AND BLUE LIGHT FUYAO GLASS IND GROUP CO LTD (CN) 2025-11-26 EP disclosed
EP-0001096-A2 Flame retardant polycarbonate blends Mobay Chemical Corporation (US) 1979-03-21 EP disclosed
US-3957666-A HYDRAULIC FLUIDS, HEAT TRANSFER FLUIDS MONSANTO COMPANY (US) 1976-05-18 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030164286-A1 Apparatus for decomposing halogenated aliphatic hydrocarbon compounds or aromatic compounds AHR, ARNT, TRPA1 ALOX5 1532/4885TAAR1 1006/4885ESR2 3033/4885
US-11981616-B2 Method for preparing 3,3′-diaminobenzidine CA3, DDT, DNPEP ALOX5 2806/4885TAAR1 1902/4885ESR2 1286/4885
US-20240109835-A1 METHOD FOR PREPARING 3,3'-DIAMINOBENZIDINE CA3, DDT, DNPEP ALOX5 2433/4885TAAR1 1866/4885ESR2 1346/4885
US-20020130030-A1 METHOD OF DECOMPOSING HALOGENATED ALIPHATIC HYDROCARBON COMPOUNDS OR AROMATIC COMPOUNDS AND APPARATUS TO BE USED FOR THE SAME AS WELL AS METHOD OF CLARIFYING EXHAUST GAS AND APPARATUS TO BE USED FOR THE SAME AHR, ARNT, TRPA1 ALOX5 1480/4885TAAR1 891/4885ESR2 1116/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.