Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | ALOX5 | P09917 | 3/20 | 0.51 |
| ▸ | MEN1 | O00255 | 5/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.48 |
| ▸ | MAPT | P10636 | 4/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.48 |
| ▸ | HTT | P42858 | 3/20 | 0.48 |
| ▸ | LMNA | P02545 | 3/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.43 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1099548 | 0.85 | MEN1 (0.55) | ALDH1A1ALOX5MEN1KMT2AMAPT | |
| SCHEMBL31191372 | 0.85 | ALDH1A1 (0.53) | ALDH1A1ALOX5MEN1KMT2AMAPT | |
| SCHEMBL419102 | 0.83 | ALOX5 (0.55) | ALDH1A1ALOX5MEN1KMT2AMAPT | |
| SCHEMBL1719601 | 0.83 | SMN1; SMN2 (0.68) | ALDH1A1TSHRALOX5MEN1KMT2A | |
| SCHEMBL16952226 | 0.83 | ALOX5 (0.50) | ALDH1A1ALOX5MEN1KMT2AMAPT | |
| SCHEMBL16396350 | 0.83 | MAOB (0.53) | ALDH1A1ALOX5MEN1KMT2AMAPT | |
| Hydrochloric Acid SCHEMBL29868255 | 0.82 | SMN1; SMN2 (0.66) | ALDH1A1TSHRALOX5MEN1KMT2A | |
| SCHEMBL54880 | 0.82 | ALDH1A1 (0.66) | ALDH1A1TSHRALOX5MEN1KMT2A | |
| SCHEMBL728757 | 0.82 | ALDH1A1 (0.66) | ALDH1A1TSHRALOX5MEN1KMT2A | |
| SCHEMBL3580457 | 0.81 | KMT2A (0.51) | ALDH1A1ALOX5MEN1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4720034-A1 | NOVEL COMPOUNDS TO TREAT VIRAL INFECTIONS | Zydus Lifesciences Limited (IN) | 2026-04-08 | — | — | EP | disclosed |
| US-20250154140-A1 | ISOQUINOLINE DERIVATIVES AS INHIBITORS OF BAX AND/OR BAK, COMPOSITIONS AND USES THEREOF | Sunnybrook Research Institute (CA) | 2025-05-15 | — | — | US | disclosed |
| EP-4479383-A1 | ISOQUINOLINE DERIVATIVES AS INHIBITORS OF BAX AND/OR BAK, COMPOSITIONS AND USES THEREOF | Sunnybrook Research Institute (CA) | 2024-12-25 | — | — | EP | disclosed |
| WO-2024252254-A1 | NOVEL COMPOUNDS TO TREAT VIRAL INFECTIONS | ZYDUS LIFESCIENCES LIMITED (IN) | 2024-12-12 | — | — | WO | disclosed |
| CN-119013259-A | Isoquinoline derivatives as inhibitors of BAX and/or BAK, compositions and uses thereof | 森尼布鲁克研究院 | 2024-11-22 | — | — | CN | disclosed |
| WO-2023155019-A1 | ISOQUINOLINE DERIVATIVES AS INHIBITORS OF BAX AND/OR BAK, COMPOSITIONS AND USES THEREOF | Sunnybrook Research Institute (CA) | 2023-08-24 | — | — | WO | disclosed |
| EP-3604299-B1 | CHEMICAL COMPOUND USEFUL AS INTERMEDIATE FOR PREPARING A CATECHOL-0-METHYL TRANSFERASE INHIBITOR | BIAL PORTELA & CA SA (PT) | 2023-07-26 | — | — | EP | disclosed |
| EP-3514153-B1 | PYRIMIDINE COMPOUND AND PHARMACEUTICAL USE THEREOF | HANMI PHARM IND CO LTD (KR) | 2021-07-07 | — | — | EP | disclosed |
| EP-3789386-A1 | PYRIMIDINE COMPOUND AND PHARMACEUTICAL USE THEREOF | Hanmi Pharm. Co., Ltd. (KR) | 2021-03-10 | — | — | EP | disclosed |
| US-10562912-B2 | Heterocyclic derivatives and use thereof | C&C RESEARCH LABORATORIES (KR) | 2020-02-18 | — | — | US | disclosed |
| US-10280154-B2 | Pyrimidine compound and pharmaceutical use thereof | HANMI PHARM. CO., LTD. (KR) | 2019-05-07 | — | — | US | disclosed |
| US-20190127353-A1 | PYRIMIDINE COMPOUND AND PHARMACEUTICAL USE THEREOF | HANMI PHARM. CO., LTD. (KR) | 2019-05-02 | — | — | US | disclosed |
| US-20190127353-A1 | PYRIMIDINE COMPOUND AND PHARMACEUTICAL USE THEREOF | HANMI PHARM. CO., LTD. (KR) | 2019-05-02 | — | — | US | disclosed |
| US-20190031643-A1 | PYRIMIDINE COMPOUND AND PHARMACEUTICAL USE THEREOF | HANMI PHARM. CO., LTD. (KR) | 2019-01-31 | — | — | US | disclosed |
| US-20190031643-A1 | PYRIMIDINE COMPOUND AND PHARMACEUTICAL USE THEREOF | HANMI PHARM. CO., LTD. (KR) | 2019-01-31 | — | — | US | disclosed |
| WO-2018139903-A1 | PYRIMIDINE COMPOUND AND PHARMACEUTICAL USE THEREOF | 한미약품 주식회사 | 2018-08-02 | — | — | WO | disclosed |
| EP-3004057-B1 | HETEROCYCLIC DERIVATIVES AND THEIR USE AS STAT 3 INHIBITORS | C&C RES LAB (KR) | 2018-07-25 | — | — | EP | disclosed |
| US-20160108056-A1 | HETEROCYCLIC DERIVATIVES AND USE THEREOF | C&C RESEARCH LABORATORIES (KR) | 2016-04-21 | — | — | US | disclosed |
| EP-3004057-A1 | HETEROCYCLIC DERIVATIVES AND USE THEREOF | C&C Research Laboratories (KR) | 2016-04-13 | — | — | EP | disclosed |
| WO-2014196793-A1 | HETEROCYCLIC DERIVATIVES AND USE THEREOF | C&C RESEARCH LABORATORIES (KR) | 2014-12-11 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10280154-B2 | Pyrimidine compound and pharmaceutical use thereof | TYMP, DPYD, TYMS | ALDH1A1 389/4885TSHR 4233/4885ALOX5 1516/4885 |
| US-20190031643-A1 | PYRIMIDINE COMPOUND AND PHARMACEUTICAL USE THEREOF | TYMP, DPYD, TYMS | ALDH1A1 389/4885TSHR 4233/4885ALOX5 1516/4885 |
| US-20190127353-A1 | PYRIMIDINE COMPOUND AND PHARMACEUTICAL USE THEREOF | TYMP, DPYD, TYMS | ALDH1A1 389/4885TSHR 4233/4885ALOX5 1516/4885 |
| US-20160108056-A1 | HETEROCYCLIC DERIVATIVES AND USE THEREOF | STAT3, JAK2, STAT5A | ALDH1A1 1646/4885TSHR 1536/4885ALOX5 2874/4885 |
| US-10562912-B2 | Heterocyclic derivatives and use thereof | STAT3, JAK2, STAT5A | ALDH1A1 1646/4885TSHR 1536/4885ALOX5 2874/4885 |
| US-20250154140-A1 | ISOQUINOLINE DERIVATIVES AS INHIBITORS OF BAX AND/OR BAK, COMPOSITIONS AND USES THEREOF | BAK1, BAX, BCL2 | ALDH1A1 3801/4885TSHR 4782/4885ALOX5 2725/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.