Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 5/20 | 0.43 |
| ▸ | HTR2A | P28223 | 6/20 | 0.41 |
| ▸ | HTR2C | P28335 | 6/20 | 0.41 |
| ▸ | HTR2B | P41595 | 6/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 5/20 | 0.41 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.36 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.36 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.36 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.36 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.36 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.36 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.36 |
| ▸ | KDM1A | O60341 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL352937 | 0.79 | SIGMAR1 (0.47) | SIGMAR1HTR2AHTR2CHTR2BHRH3 | |
| SCHEMBL29607922 | 0.76 | HTR2A (0.39) | SIGMAR1HTR2AHTR2CHTR2BHRH3 | |
| SCHEMBL8130206 | 0.76 | HTR2A (0.39) | SIGMAR1HTR2AHTR2CHTR2BHRH3 | |
| SCHEMBL461946 | 0.76 | HTR2A (0.54) | SIGMAR1HTR2AHTR2CHTR2BHRH3 | |
| SCHEMBL7545824 | 0.74 | HTR2A (0.53) | SIGMAR1HTR2AHTR2CHTR2BHRH3 | |
| SCHEMBL2766554 | 0.73 | HTR2A (0.50) | SIGMAR1HTR2AHTR2CHTR2BHRH3 | |
| SCHEMBL29723594 | 0.73 | HTR2A (0.50) | SIGMAR1HTR2AHTR2CHTR2BHRH3 | |
| SCHEMBL7932553 | 0.72 | SIGMAR1 (0.53) | SIGMAR1 | |
| Ammonia Solution, Strong SCHEMBL2786789 | 0.71 | HTR2A (0.49) | SIGMAR1HTR2AHTR2CHTR2BHRH3 | |
| SCHEMBL7376647 | 0.70 | HTR2C (0.42) | SIGMAR1HTR2AHTR2CHTR2BHRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3022233-A1 | CYCLOPROPYL SUBSTITUTED METALLOCENE CATALYSTS | ExxonMobil Chemical Patents Inc. (US) | 2016-05-25 | — | — | EP | disclosed |
| WO-2015009473-A1 | CYCLOPROPYL SUBSTITUTED METALLOCENE CATALYSTS | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2015-01-22 | — | — | WO | disclosed |