Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 6/20 | 0.53 |
| ▸ | HTR2C | P28335 | 6/20 | 0.53 |
| ▸ | HTR2B | P41595 | 6/20 | 0.53 |
| ▸ | HRH3 | Q9Y5N1 | 5/20 | 0.53 |
| ▸ | SIGMAR1 | Q99720 | 8/20 | 0.45 |
| ▸ | PRCP | P42785 | 1/20 | 0.42 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.39 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL461946 | 0.98 | HTR2A (0.54) | HTR2AHTR2CHTR2BHRH3SIGMAR1 | |
| SCHEMBL352937 | 0.85 | SIGMAR1 (0.47) | HTR2AHTR2CHTR2BHRH3SIGMAR1 | |
| SCHEMBL22304223 | 0.82 | HTR2A (0.51) | HTR2AHTR2CHTR2BHRH3SIGMAR1 | |
| SCHEMBL2064332 | 0.80 | SIGMAR1 (0.56) | HTR2AHTR2CHTR2BHRH3SIGMAR1 | |
| SCHEMBL10785005 | 0.80 | SIGMAR1 (0.60) | HTR2AHTR2CHTR2BHRH3SIGMAR1 | |
| SCHEMBL11860825 | 0.79 | HTR2A (0.45) | HTR2AHTR2CHTR2BHRH3SIGMAR1 | |
| SCHEMBL21924071 | 0.78 | SIGMAR1 (0.63) | HTR2AHTR2CHTR2BHRH3SIGMAR1 | |
| SCHEMBL6542145 | 0.78 | SIGMAR1 (0.63) | HTR2AHTR2CHTR2BHRH3SIGMAR1 | |
| SCHEMBL4661810 | 0.78 | SIGMAR1 (0.63) | HTR2AHTR2CHTR2BHRH3SIGMAR1 | |
| SCHEMBL30285859 | 0.78 | SIGMAR1 (0.63) | HTR2AHTR2CHTR2BHRH3SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0900228-B1 | A METHOD FOR PRODUCING OCTAHYDROFLUORENYL METAL COMPLEXES | DOW CHEMICAL CO (US) | 2002-06-12 | — | — | EP | disclosed |
| EP-0900228-A1 | A METHOD FOR PRODUCING OCTAHYDROFLUORENYL METAL COMPLEXES | THE DOW CHEMICAL COMPANY (US) | 1999-03-10 | — | — | EP | disclosed |
| WO-1997041134-A1 | A METHOD FOR PRODUCING OCTAHYDROFLUORENYL METAL COMPLEXES | THE DOW CHEMICAL COMPANY (US) | 1997-11-06 | — | — | WO | disclosed |