Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TGFBR1 | P36897 | 3/20 | 0.44 |
| ▸ | SLC1A1 | P43005 | 4/20 | 0.42 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.40 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.38 |
| ▸ | SLC7A11 | Q9UPY5 | 1/20 | 0.38 |
| ▸ | SLC1A3 | P43003 | 4/20 | 0.36 |
| ▸ | SLC1A2 | P43004 | 4/20 | 0.36 |
| ▸ | MME | P08473 | 1/20 | 0.36 |
| ▸ | GRIK1 | P39086 | 2/20 | 0.35 |
| ▸ | GRM8 | O00222 | 1/20 | 0.35 |
| ▸ | GRM6 | O15303 | 1/20 | 0.35 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.35 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.35 |
| ▸ | GSR | P00390 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | GRM5 | P41594 | 1/20 | 0.35 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.35 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.35 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.35 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Serine SCHEMBL16397814 | 1.00 | TGFBR1 (0.44) | TGFBR1SLC1A1SLC7A5PTGS1SLC7A11 | |
| SCHEMBL170982 | 0.87 | — | — | |
| SCHEMBL181375 | 0.87 | — | — | |
| SCHEMBL163350 | 0.87 | — | — | |
| D-Leucine SCHEMBL3416402 | 0.85 | SLC7A5 (0.64) | TGFBR1SLC1A1SLC7A5SLC1A3SLC1A2 | |
| Hydrochloric Acid SCHEMBL2852737 | 0.84 | — | — | |
| Serine SCHEMBL28359073 | 0.84 | SLC1A1 (0.50) | SLC1A1SLC7A5PTGS1SLC7A11SLC1A3 | |
| Serine SCHEMBL28359075 | 0.84 | SLC1A1 (0.50) | SLC1A1SLC7A5PTGS1SLC7A11SLC1A3 | |
| Hydrochloric Acid SCHEMBL2852741 | 0.84 | — | — | |
| Hydrochloric Acid SCHEMBL28497287 | 0.84 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3022220-A1 | PROTEASE-RESISTANT PEPTIDE LIGANDS | North Carolina State University (US) | 2016-05-25 | — | — | EP | disclosed |
| WO-2015009701-A1 | PROTEASE-RESISTANT PEPTIDE LIGANDS | NORTH CAROLINA STATE UNIVERSITY (US) | 2015-01-22 | — | — | WO | disclosed |