Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.64 |
| ▸ | SLC1A3 | P43003 | 4/20 | 0.52 |
| ▸ | SLC1A2 | P43004 | 4/20 | 0.52 |
| ▸ | MME | P08473 | 5/20 | 0.46 |
| ▸ | SLC1A1 | P43005 | 4/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | LAP3 | P28838 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Leucine SCHEMBL3052691 | 0.89 | SLC7A5 (0.69) | SLC7A5SLC1A3SLC1A2SLC1A1ALDH1A1 | |
| Serine SCHEMBL16397818 | 0.85 | TGFBR1 (0.44) | SLC7A5SLC1A3SLC1A2MMESLC1A1 | |
| Serine SCHEMBL16397814 | 0.85 | TGFBR1 (0.44) | SLC7A5SLC1A3SLC1A2MMESLC1A1 | |
| Leucine SCHEMBL26113177 | 0.83 | ALDH1A1 (0.62) | SLC7A5SLC1A3SLC1A2MMESLC1A1 | |
| Leucine SCHEMBL5520318 | 0.81 | SLC7A5 (0.82) | SLC7A5SLC1A3SLC1A2SLC1A1LAP3 | |
| Leucine SCHEMBL4011464 | 0.81 | SLC7A5 (0.82) | SLC7A5SLC1A3SLC1A2SLC1A1LAP3 | |
| Leucine SCHEMBL5520323 | 0.81 | SLC7A5 (0.82) | SLC7A5SLC1A3SLC1A2SLC1A1LAP3 | |
| Leucine SCHEMBL25241602 | 0.80 | SLC7A5 (1.00) | SLC7A5SLC1A3SLC1A2SLC1A1 | |
| Leucine SCHEMBL8568060 | 0.80 | SLC7A5 (1.00) | SLC7A5SLC1A3SLC1A2SLC1A1 | |
| Leucine SCHEMBL175940 | 0.80 | SLC7A5 (1.00) | SLC7A5SLC1A3SLC1A2SLC1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3472192-A1 | SPIDER VENOM PEPTIDES AND METHODS OF USE FOR MODULATING SODIUM CHANNELS. | The University of Queensland (AU) | 2019-04-24 | — | — | EP | disclosed |
| EP-3411061-A1 | PROTEINACEOUS COMPOUNDS AND USES THEREFOR | University of Canberra (AU) | 2018-12-12 | — | — | EP | disclosed |
| EP-3387007-A1 | PROTEINACEOUS MOLECULES AND METHODS OF USE | The University of Queensland (AU) | 2018-10-17 | — | — | EP | disclosed |
| WO-2017219081-A1 | SPIDER VENOM PEPTIDES AND METHODS OF USE FOR MODULATING SODIUM CHANNELS. | THE UNIVERSITY OF QUEENSLAND (AU) | 2017-12-28 | — | — | WO | disclosed |
| WO-2017132728-A1 | PROTEINACEOUS COMPOUNDS AND USES THEREFOR | UNIVERSITY OF CANBERRA (AU) | 2017-08-10 | — | — | WO | disclosed |
| WO-2017096431-A1 | PROTEINACEOUS MOLECULES AND METHODS OF USE | THE UNIVERSITY OF QUEENSLAND (AU) | 2017-06-15 | — | — | WO | disclosed |
| EP-2231172-A1 | IMMUNOMODULATING COMPOSITIONS AND USES THEREFOR | Opal Therapeutics Pty Ltd (AU) | 2010-09-29 | — | — | EP | disclosed |
| WO-2009089568-A1 | IMMUNOMODULATING COMPOSITIONS AND USES THEREFOR | OPAL THERAPEUTICS PTY LTD (AU) | 2009-07-23 | — | — | WO | disclosed |