SCHEMBL1639809

SCHEMBL1639809

CO[Si](C)(OC)c1ccccc1-c1ccccc1[Si](C)(OC)OC

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 8/20 0.36
SMN1; SMN2 Q16637 4/20 0.36
RAB9A P51151 3/20 0.36
MAPT P10636 3/20 0.36
TDP1 Q9NUW8 3/20 0.36
CDC25A P30304 2/20 0.36
CDC25B P30305 2/20 0.36
KDM4E B2RXH2 2/20 0.36
CYP1A2 P05177 2/20 0.36
CYP2C19 P33261 2/20 0.36
TP53 P04637 2/20 0.36
ALOX15 P16050 2/20 0.36
HPGD P15428 2/20 0.36
MAP2K7 O14733 1/20 0.36
GMNN O75496 1/20 0.36
LMNA P02545 1/20 0.36
POLB P06746 1/20 0.36
CYP3A4 P08684 1/20 0.36
CYP2D6 P10635 1/20 0.36
CYP2C9 P11712 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1639784 0.88
SCHEMBL30473475 0.87 CA4 (0.36) ALDH1A1SMN1; SMN2RAB9AKDM4ECYP1A2
SCHEMBL1639954 0.87 CA4 (0.36) ALDH1A1SMN1; SMN2RAB9AKDM4ECYP1A2
SCHEMBL7186109 0.87 MAPT (0.38) ALDH1A1SMN1; SMN2RAB9AMAPTKDM4E
SCHEMBL5872429 0.78 TSHR (0.41) ALDH1A1SMN1; SMN2RAB9ATDP1CYP1A2
SCHEMBL1109638 0.77 ALDH1A1 (0.37) ALDH1A1SMN1; SMN2RAB9AMAPTTDP1
SCHEMBL820792 0.76 ALDH1A1 (0.43) ALDH1A1SMN1; SMN2RAB9AMAPTTDP1
SCHEMBL29444220 0.76 TSHR (0.43) ALDH1A1SMN1; SMN2RAB9AMAPTTDP1
SCHEMBL29264599 0.76 TSHR (0.39) ALDH1A1SMN1; SMN2RAB9AMAPTTDP1
SCHEMBL18043733 0.76 TSHR (0.43) ALDH1A1SMN1; SMN2RAB9AMAPTTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1391476-B1 PHOTOREACTIVE COMPOSITION SEKISUI CHEMICAL CO LTD (JP) 2015-12-09 EP disclosed
US-8536242-B2 Photocurable composition SEKISUI CHEMICAL CO., LTD. (JP) 2013-09-17 US disclosed
US-20110097669-A1 PHOTOCURABLE COMPOSITION SEKISUI CHEMICAL CO., LTD. (JP) 2011-04-28 US disclosed
US-7312013-B2 Photoreactive composition SEKISUI CHEMICAL CO., LTD. (JP) 2007-12-25 US disclosed
US-20040202956-A1 a photocurable mixture of a hydrolyzable metal (silyl) compound and a reaction, polymerization or crosslinking promoter; curing; adhesives, seals, semiconductors, dielectrics, microlenses, optical fibers, color filters, gas permeable films SEKISUI CHEMICAL CO., LTD. (JP) 2004-10-14 US disclosed
EP-1391476-A1 PHOTOREACTIVE COMPOSITION SEKISUI CHEMICAL CO., LTD. (JP) 2004-02-25 EP disclosed