Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.48 |
| ▸ | NPC1 | O15118 | 4/20 | 0.48 |
| ▸ | RAB9A | P51151 | 3/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | CASP1 | P29466 | 1/20 | 0.48 |
| ▸ | HBB | P68871 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | JUN | P05412 | 1/20 | 0.46 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.46 |
| ▸ | CYP1A1 | P04798 | 2/20 | 0.45 |
| ▸ | CYP1B1 | Q16678 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5237017 | 1.00 | MAPT (0.48) | MAPTNPC1RAB9ASMN1; SMN2CYP1A2 | |
| SCHEMBL210914 | 0.84 | MAOB (0.33) | MAPTNPC1RAB9ASMN1; SMN2CYP1A2 | |
| SCHEMBL107198 | 0.84 | MAPT (0.61) | MAPTNPC1RAB9ASMN1; SMN2CYP1A2 | |
| SCHEMBL152100 | 0.84 | MAOB (0.33) | MAPTNPC1RAB9ASMN1; SMN2CYP1A2 | |
| SCHEMBL138489 | 0.84 | MAPT (0.61) | MAPTNPC1RAB9ASMN1; SMN2CYP1A2 | |
| SCHEMBL135604 | 0.81 | MAPT (0.65) | MAPTNPC1RAB9ASMN1; SMN2CYP1A2 | |
| SCHEMBL31175769 | 0.81 | MAPT (0.58) | MAPTNPC1RAB9ASMN1; SMN2CYP1A2 | |
| SCHEMBL9966009 | 0.81 | MAPT (0.65) | MAPTNPC1RAB9ASMN1; SMN2CYP1A2 | |
| SCHEMBL10495642 | 0.79 | KMT2A (0.41) | MAPTNPC1RAB9ASMN1; SMN2HPGD | |
| SCHEMBL10452019 | 0.76 | MAPT (0.54) | MAPTNPC1RAB9ASMN1; SMN2CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9707540-B2 | Metal-organic materials and method for preparation | YEDA RESEARCH AND DEVELOPMENT CO. LTD. (IL) | 2017-07-18 | — | — | US | disclosed |
| US-9611218-B2 | Metal-organic materials and method for preparation | YEDA RESEARCH AND DEVELOPMENT CO., LTD. (IL) | 2017-04-04 | — | — | US | disclosed |
| US-20160271582-A1 | METAL-ORGANIC MATERIALS AND METHOD FOR PREPARATION | YEDA RESEARCH AND DEVELOPMENT CO. LTD. (IL) | 2016-09-22 | — | — | US | disclosed |
| CN-105873987-A | Metal organic material and preparation method | 耶达研究及发展有限公司 | 2016-08-17 | — | — | CN | disclosed |
| US-20160152568-A1 | METAL-ORGANIC MATERIALS AND METHOD FOR PREPARATION | YEDA RESEARCH AND DEVELOPMENT CO. LTD. (IL) | 2016-06-02 | — | — | US | disclosed |
| EP-3022250-A1 | METAL-ORGANIC MATERIALS AND METHOD FOR PREPARATION | YEDA RESEARCH AND DEVELOPMENT CO. LTD., AT THE WEI (IL) | 2016-05-25 | — | — | EP | disclosed |
| WO-2015008280-A1 | METAL-ORGANIC MATERIALS AND METHOD FOR PREPARATION | YEDA RESEARCH AND DEVELOPMENT CO. LTD AT THE WEIZMANN INSTITUTE OF SCIENCE (IL) | 2015-01-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160152568-A1 | METAL-ORGANIC MATERIALS AND METHOD FOR PREPARATION | CACNG7, CACNG3, PSEN2 | MAPT 645/4885NPC1 3579/4885RAB9A 3631/4885 |
| US-20160271582-A1 | METAL-ORGANIC MATERIALS AND METHOD FOR PREPARATION | CACNG7, CACNG3, CACNA1I | MAPT 668/4885NPC1 3260/4885RAB9A 3803/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.