SCHEMBL138489

SCHEMBL138489

C(=Cc1ccncc1)c1ccncc1

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 7/20 0.61
NPC1 O15118 4/20 0.61
RAB9A P51151 3/20 0.61
SMN1; SMN2 Q16637 3/20 0.61
CYP1A2 P05177 2/20 0.61
HPGD P15428 2/20 0.61
KDM4E B2RXH2 2/20 0.61
MEN1 O00255 1/20 0.61
ALOX15 P16050 1/20 0.61
CASP1 P29466 1/20 0.61
HBB P68871 1/20 0.61
KMT2A Q03164 1/20 0.61
CYP3A4 P08684 1/20 0.61
CYP2D6 P10635 1/20 0.61
CYP2C9 P11712 1/20 0.61
CYP2C19 P33261 1/20 0.61
JUN P05412 1/20 0.59
NFKB1 P19838 1/20 0.59
CYP1A1 P04798 2/20 0.56
CYP1B1 Q16678 2/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL107198 1.00 MAPT (0.61) MAPTNPC1RAB9ASMN1; SMN2CYP1A2
SCHEMBL9966009 0.97 MAPT (0.65) MAPTNPC1RAB9ASMN1; SMN2CYP1A2
SCHEMBL31175769 0.97 MAPT (0.58) MAPTNPC1RAB9ASMN1; SMN2CYP1A2
SCHEMBL135604 0.97 MAPT (0.65) MAPTNPC1RAB9ASMN1; SMN2CYP1A2
SCHEMBL13907337 0.91 MAPT (0.54) MAPTNPC1RAB9ASMN1; SMN2CYP1A2
SCHEMBL15901869 0.91 CYP1A2 (0.61) MAPTNPC1RAB9ASMN1; SMN2CYP1A2
SCHEMBL13907330 0.91 CYP1A2 (0.61) MAPTNPC1RAB9ASMN1; SMN2CYP1A2
SCHEMBL10452019 0.91 MAPT (0.54) MAPTNPC1RAB9ASMN1; SMN2CYP1A2
SCHEMBL1880739 0.88 CYP11B2 (0.62) MAPTNPC1RAB9ASMN1; SMN2CYP1A2
SCHEMBL1509973 0.88 CYP11B2 (0.62) MAPTNPC1RAB9ASMN1; SMN2CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1496 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12636634-B2 Fluorinated MOF materials having rectangular channels, method of synthesizing MOF materials and methods of using MOF materials including for CO2 capture KING ABDULLAH UNIVERSITY OF SCIENCE AND TECHNOLOGY (SA) 2026-05-26 US claimed
US-12576387-B2 Porous metal-organic framework, method for producing the same, adsorbent, and method for separating carbon dioxide KABUSHIKI KAISHA TOSHIBA (JP) 2026-03-17 US claimed
EP-4649543-A1 TRANSFORMABLE BINDER COMPOSITION PROVIDING A PRINTABLE ELECTROLYTE COMPOSITION RISE Research Institutes of Sweden AB (SE) 2025-11-19 EP claimed
EP-4578530-A1 PROCESS FOR THE SEPARATION OF KRYPTON FROM A WASTE GAS STREAM Immaterial Ltd (GB) 2025-07-02 EP claimed
WO-2025118109-A1 METHOD FOR PREPARING NANO-FLAKE CALCIUM SULFATE FROM PHOSPHOGYPSUM, NANO-FLAKE CALCIUM SULFATE AND USE THEREOF 广东邦普循环科技有限公司 2025-06-12 WO claimed
CN-119977641-A Method for synchronously treating kitchen waste and garden waste by using complex enzyme 上海交通大学 2025-05-13 CN claimed
CN-119955112-A MOCPs-Ag crystal material and preparation method and application thereof 福建师范大学 2025-05-09 CN claimed
CN-116178247-B Method for synthesizing tetrapyridyl cyclobutane 中国科学院化学研究所 2025-04-08 CN claimed
CN-116217953-B Zinc-based metal-organic framework material with bacillus anthracis biomarker fluorescent recognition and preparation method thereof 江西省科学院应用化学研究所 2025-03-25 CN claimed
CN-119145073-B Antistatic antibacterial fiber and preparation method thereof 江苏瑞爱福纺织科技有限公司 2025-03-11 CN claimed
US-5563014-A SOFTENABLE LAYER CONTAINIG PHOTOSENSITIVE MARKING MATERIAL; TRANSPARENTIZING AGENT XEROX CORPORATION (US) 1996-10-08 US claimed
US-5514505-A SELECTIVE TRANSPARENTIZATION OF PHOTOSENSITIVE MIGRATION MARKING PARTICLES EMBEDDED NEAR THE SURFACE OF A SOFTENABLE LAYER SUPPORTED BY AN ELECTROCONDUCTIVE SUBSTRATE XEROX CORPORATION (US) 1996-05-07 US claimed
EP-0338504-B1 Photosensitive member for electrophotography CANON KK (JP) 1994-08-24 EP claimed
US-5008168-A Trimethyl trihdroxyphenyl substituted benzene, triphenyl phosp hite CANON KABUSHIKI KAISHA (JP) 1991-04-16 US claimed
EP-0397474-A2 Photosensitive composition KABUSHIKI KAISHA TOSHIBA (JP) 1990-11-14 EP claimed
US-4880466-A PYRIDINE, QUINOLINE OR ISOQUINOLINE COMPOUND AND NITROCELLULOSE EDWARD WECK INCORPORATED (US) 1989-11-14 US claimed
EP-0338504-A2 Photosensitive member for electrophotography CANON KABUSHIKI KAISHA (JP) 1989-10-25 EP claimed
EP-0035842-B1 CATHODE MATERIALS FOR ELECTROCHEMICAL CELLS AND CELLS CONTAINING THEM MEDTRONIC, INC. (US) 1986-01-02 EP claimed
EP-0035842-A1 Cathode materials for electrochemical cells and cells containing them MEDTRONIC, INC. (US) 1981-09-16 EP claimed
US-4278745-A IODINE, 2 PYRIDINE-BASED COMPOUNDS MEDTRONIC, INC. (US) 1981-07-14 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12636634-B2 Fluorinated MOF materials having rectangular channels, method of synthesizing MOF materials and methods of using MOF materials including for CO2 capture MLX, BMP4, F13B MAPT 4241/4885NPC1 3006/4885RAB9A 1857/4885
US-12576387-B2 Porous metal-organic framework, method for producing the same, adsorbent, and method for separating carbon dioxide OXGR1, TET1, MT-CO2 MAPT 2696/4885NPC1 3859/4885RAB9A 4801/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.