SCHEMBL9966009

SCHEMBL9966009

C(=C/c1ccc(/C=C/c2ccncc2)cc1)\c1ccncc1

nearest known ligand 0.65

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 5/20 0.65
NPC1 O15118 4/20 0.65
RAB9A P51151 3/20 0.65
SMN1; SMN2 Q16637 3/20 0.65
HPGD P15428 2/20 0.65
CYP1A2 P05177 2/20 0.65
MEN1 O00255 1/20 0.65
ALOX15 P16050 1/20 0.65
CASP1 P29466 1/20 0.65
HBB P68871 1/20 0.65
KMT2A Q03164 1/20 0.65
KDM4E B2RXH2 1/20 0.65
CYP3A4 P08684 1/20 0.65
CYP2D6 P10635 1/20 0.65
CYP2C9 P11712 1/20 0.65
CYP2C19 P33261 1/20 0.65
KDM1A O60341 1/20 0.58
HDAC1 Q13547 1/20 0.58
HDAC6 Q9UBN7 1/20 0.58
JUN P05412 1/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL135604 1.00 MAPT (0.65) MAPTNPC1RAB9ASMN1; SMN2HPGD
SCHEMBL107198 0.97 MAPT (0.61) MAPTNPC1RAB9ASMN1; SMN2HPGD
SCHEMBL138489 0.97 MAPT (0.61) MAPTNPC1RAB9ASMN1; SMN2HPGD
SCHEMBL31175769 0.93 MAPT (0.58) MAPTNPC1RAB9ASMN1; SMN2HPGD
SCHEMBL24759909 0.89 CYP11B2 (0.60) MAPTNPC1RAB9ASMN1; SMN2HPGD
SCHEMBL9928791 0.89 CYP17A1 (0.62) MAPTNPC1RAB9ASMN1; SMN2HPGD
SCHEMBL9928792 0.89 CYP17A1 (0.62) MAPTNPC1RAB9ASMN1; SMN2HPGD
SCHEMBL15901869 0.88 CYP1A2 (0.61) MAPTNPC1RAB9ASMN1; SMN2HPGD
SCHEMBL13907337 0.88 MAPT (0.54) MAPTNPC1RAB9ASMN1; SMN2HPGD
SCHEMBL10452019 0.88 MAPT (0.54) MAPTNPC1RAB9ASMN1; SMN2HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 43 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20150303390-A1 SEQUENCE DEPENDENT ASSEMBLY TO CONTROL MOLECULAR INTERFACE PROPERTIES FOR MEMORY DEVICES, SOLAR CELLS AND MOLECULAR DIODES YEDA RESEARCH AND DEVELOPMENT CO. LTD. (IL) 2015-10-22 US claimed
EP-2909871-A2 SEQUENCE DEPENDENT ASSEMBLY TO CONTROL MOLECULAR INTERFACE PROPERTIES FOR MEMORY DEVICES, SOLAR CELLS AND MOLECULAR DIODES Yeda Research and Development Co. Ltd (IL) 2015-08-26 EP claimed
WO-2014061018-A2 SEQUENCE DEPENDENT ASSEMBLY TO CONTROL MOLECULAR INTERFACE PROPERTIES FOR MEMORY DEVICES, SOLAR CELLS AND MOLECULAR DIODES YEDA RESEARCH AND DEVELOPMENT CO. LTD AT THE WEIZMANN INSTITUTE OF SCIENCE (IL) 2014-04-24 WO claimed
WO-2025051659-A1 UV-VIS CURABLE SECURITY INKS COMPRISING TAGS AND SECURITY FEATURES OBTAINED THEREOF SICPA HOLDING SA (CH) 2025-03-13 WO disclosed
WO-2025051658-A1 UV-VIS CURABLE SECURITY INKS COMPRISING TAGS AND SECURITY FEATURES OBTAINED THEREOF SICPA HOLDING SA (CH) 2025-03-13 WO disclosed
US-12216059-B2 Method for manufacturing surface enhanced Raman spectroscopy tags SICPA HOLDING SA (CH) 2025-02-04 US disclosed
EP-3999834-B1 METHOD FOR MANUFACTURING SURFACE ENHANCED RAMAN SPECTROSCOPY TAGS SICPA HOLDING SA (CH) 2024-10-23 EP disclosed
US-20230322781-A1 RING-IN-RING COMPLEXES EXHIBITING TUNABLE MULTICOLOR PHOTOLUMINESCENCE NORTHWESTERN UNIVERSITY 2023-10-12 US disclosed
US-20230322781-A1 RING-IN-RING COMPLEXES EXHIBITING TUNABLE MULTICOLOR PHOTOLUMINESCENCE NORTHWESTERN UNIVERSITY 2023-10-12 US disclosed
US-20220268705-A1 METHOD FOR MANUFACTURING SURFACE ENHANCED RAMAN SPECTROSCOPY TAGS SICPA HOLDING SA (CH) 2022-08-25 US disclosed
EP-3999834-A1 METHOD FOR MANUFACTURING SURFACE ENHANCED RAMAN SPECTROSCOPY TAGS Sicpa Holding SA (CH) 2022-05-25 EP disclosed
EP-2091077-B1 ELECTRODE COATING MATERIAL, ELECTRODE STRUCTURE AND SEMICONDUCTOR DEVICE SONY CORP (JP) 2014-01-29 EP disclosed
US-20120194894-A1 ELECTROCHROMIC COMPOUND, ELECTROCHROMIC COMPOSITION, AND DISPLAY ELEMENT RICOH COMPANY, LTD. (JP) 2012-08-02 US disclosed
US-20120194894-A1 ELECTROCHROMIC COMPOUND, ELECTROCHROMIC COMPOSITION, AND DISPLAY ELEMENT RICOH COMPANY, LTD. (JP) 2012-08-02 US disclosed
US-20120156491-A1 SERS Reporter Molecules and Methods CABOT SECURITY MATERIALS INC. (US) 2012-06-21 US disclosed
WO-2011046222-A1 ELECTROCHROMIC COMPOUND, ELECTROCHROMIC COMPOSITION, AND DISPLAY ELEMENT RICOH COMPANY, LTD. (JP) 2011-04-21 WO disclosed
US-20090082574-A1 Metallacycles and methods of making the same ACADEMIA SINICA (TW) 2009-03-26 US disclosed
US-20090082574-A1 Metallacycles and methods of making the same ACADEMIA SINICA (TW) 2009-03-26 US disclosed
US-20070258147-A1 Redox-active structures and devices utilizing the same YEDA RESEARCH & DEVELOPMENT CO., LTD. (IL) 2007-11-08 US disclosed
US-20070258147-A1 Redox-active structures and devices utilizing the same YEDA RESEARCH & DEVELOPMENT CO., LTD. (IL) 2007-11-08 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120194894-A1 ELECTROCHROMIC COMPOUND, ELECTROCHROMIC COMPOSITION, AND DISPLAY ELEMENT EED, EPX, ETV6 MAPT 2292/4885NPC1 4528/4885RAB9A 1598/4885
US-20090082574-A1 Metallacycles and methods of making the same SOD1, PMS2, MEN1 MAPT 1667/4885NPC1 813/4885RAB9A 1851/4885
US-20230322781-A1 RING-IN-RING COMPLEXES EXHIBITING TUNABLE MULTICOLOR PHOTOLUMINESCENCE PPIE, CYCS, PPIC MAPT 1385/4885NPC1 2256/4885RAB9A 1613/4885
US-20120156491-A1 SERS Reporter Molecules and Methods SRRT, MYCBP, SPR MAPT 2191/4885NPC1 2242/4885RAB9A 1597/4885
US-20070258147-A1 Redox-active structures and devices utilizing the same GPX4, GPX1, LPO MAPT 2300/4885NPC1 4837/4885RAB9A 1305/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.